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The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis [Retraction]

Authors Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X

Received 23 September 2020

Accepted for publication 23 September 2020

Published 7 October 2020 Volume 2020:13 Pages 9955—9956

DOI https://doi.org/10.2147/OTT.S283590

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Shang Y, Wang Q, Li J, et al. Onco Targets Ther.  2020;13:473– 486.


The Editor and Publisher of OncoTargets and Therapy wish to retract the published article.


The journal was notified of significantly similar images and data published in a previous article by the same authors:

IF203 induced apoptosis in human liver HepG2 cells through mitochondrial pathway. Acta Anatomica Sinica.  2011;42:340– 344 (http://jpxb.bjmu.edu.cn/EN/10.3969/j. issn.0529-1356.2011.03.010).


It was found the following images and data appeared to be duplicated across both articles, with no satisfactory explanation provided by the authors:

● Figure 1B in the recent article appeared to be the same as Figure 2 in the previous publication
● Figure 3E in the recent article appeared to be the same as Figure 3 in the previous publication
● Figure 3C in the recent article appeared to be the same as Figure 4 in the previous publication
● Figure 3E in the recent article appeared to be the same as Table 2 in the previous publication


The authors were also unable to provide the original raw data for the western blots shown in Figure 6. The editor determined the findings of the study were not supported and requested for the article to be retracted.


The authors wish to apologise for this error.


Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction.


The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

This retraction relates to this paper

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