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Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study

Authors Bourget Olivieri E, Vecchiato, Ignaccolo N, Piero Mannu, Castagna A, Aravagli L, Fontani V, Rinaldi S

Published 4 August 2011 Volume 2011:7(1) Pages 449—455

DOI https://doi.org/10.2147/NDT.S23420

Review by Single-blind

Peer reviewer comments 2


Elisabetta Bourget Olivieri1, Caterina Vecchiato1, Nunziatina Ignaccolo1, Piero Mannu2, Alessandro Castagna2, Lucia Aravagli2, Vania Fontani2, Salvatore Rinaldi2,3
1Healthcare enterprise Hospital Trust S Croce and Carle Complex Structure of Psychiatry, Cuneo, Italy; 2Rinaldi Fontani Institute, Department of Neuro Psycho Physio Pathology, Florence, Italy; 3Medical School of Occupational Medicine, University of Florence, Florence, Italy

Background: Generalized anxiety disorder (GAD) is often presented with major depression (MD). GAD-MD can be a chronic and disabling condition, and patients suffering from this disorder often respond poorly to psychopharmacological treatment and experience side effects with medication. Therefore, there is a high demand for effective nonpharmacological therapy for GAD-MD patients. The current study explores the use of a radioelectric asymmetric conveyer (REAC) device in the treatment of GAD-MD.
Methods: Participants were 24 patients diagnosed with GAD-MD being treated at a public psychiatric center. All patients were dissatisfied with their current pharmacological treatment. Patients were evaluated using the 21-item Hamilton Depression (HAM-D) rating scale and the Symptom Check List-90-Revised (SCL-90R) before and after REAC brain stimulation treatment cycles.
Results: After REAC brain stimulation treatment, all patients experienced a significant reduction in anxiety and depression. These results were confirmed by physician examination, HAM-D scores, and SCL-90R total scores.
Conclusion: These results indicate a role for REAC brain stimulation in the management of psychiatric conditions, specifically, GAD-MD comorbidity. REAC treatments are synergistic to drug therapy and appear to be helpful in reducing the side effects of medication. Future studies should evaluate the long-term effects of REAC treatment.

Keywords: anxiety disorders, depressive disorder, psychiatric somatic therapies, radioelectric asymmetric brain stimulation

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