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Prune belly syndrome: current perspectives

Authors Arlen AM, Nawaf C, Kirsch AJ

Received 14 May 2019

Accepted for publication 13 June 2019

Published 6 August 2019 Volume 2019:10 Pages 75—81


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Roosy Aulakh

Angela M Arlen,1 Cayce Nawaf,1 Andrew J Kirsch2

1Yale University School of Medicine, Department of Urology, New Haven, CT 06520, USA; 2Emory University, Children’s Healthcare of Atlanta, Atlanta, GA 30328, USA

Abstract: Prune belly syndrome (PBS) is a rare but morbid congenital disease, classically defined by a triad of cardinal features that includes cryptorchidism, urinary tract dilation and laxity of the abdominal wall musculature. Children often require numerous surgical interventions including bilateral orchidopexy as well as individually tailored urinary tract and abdominal wall reconstruction. Along with the classic features, patients with PBS often experience gastrointestinal, orthopedic, and cardiopulmonary comorbidities.

Keywords: prune-belly syndrome, cryptorchidism, urinary tract dilation, abdominal wall laxity, abdominoplasty

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