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Potential of minimally invasive procedures in the treatment of uterine fibroids: a focus on magnetic resonance-guided focused ultrasound therapy

Authors Fischer K, McDannold N, Tempany C, Jolesz F, Fennessy F

Received 13 April 2015

Accepted for publication 29 May 2015

Published 13 November 2015 Volume 2015:7 Pages 901—912


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Elie Al-Chaer

Krisztina Fischer,1–3 Nathan J McDannold,1 Clare M Tempany,1 Ferenc A Jolesz,1,† Fiona M Fennessy1,4

1Department of Radiology, 2Renal Division, 3Biomedical Engineering Division, Brigham and Women’s Hospital, 4Department of Radiology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

Ferenc A Jolesz passed away on December 31, 2014

Abstract: Minimally invasive treatment options are an important part of the uterine fibroid-treatment arsenal, especially among younger patients and in those who plan future pregnancies. This article provides an overview of the currently available minimally invasive therapy options, with a special emphasis on a completely noninvasive option: magnetic resonance-guided focused ultrasound (MRgFUS). In this review, we describe the background of MRgFUS, the patient-selection criteria for MRgFUS, and how the procedure is performed. We summarize the published clinical trial results, and review the literature on pregnancy post-MRgFUS and on the cost-effectiveness of MRgFUS.

Keywords: uterine fibroids, MRgFUS, focused ultrasound, minimally invasive treatment

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