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Oncological safety and cosmetic outcomes in oncoplastic breast conservation surgery, a review of the best level of evidence literature

Authors Campbell EJ, Romics L

Received 13 March 2017

Accepted for publication 12 June 2017

Published 4 August 2017 Volume 2017:9 Pages 521—530


Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 3

Editor who approved publication: Professor Pranela Rameshwar

Esther Jennifer Campbell,1 Laszlo Romics2,3

1Department of Plastic Surgery, Glasgow Royal Infirmary, 2Department of Surgery, New Victoria Hospital Glasgow, 3Department of Academic Surgery, Glasgow Royal Infirmary, Glasgow, Scotland, UK

Abstract: Oncoplastic breast conservation surgery (OBCS) is increasingly becoming part of routine breast cancer surgical management. OBCS may be viewed as an extension of standard breast conservation surgery for resecting tumors of larger sizes without compromising on cosmetic outcome, or as an alternative to mastectomy. High quality evidence to support the oncological safety and benefits of OBCS is lacking. This review will focus on the best available level of evidence and address key issues regarding oncological safety in OBCS, such as tumor resection margins and re-excision rates, local recurrence and patient outcome, postoperative complications and adjuvant therapy delivery, and briefly discuss cosmetic outcome in OBCS. Comparative observational studies and systematic review report no poorer outcomes compared with standard breast conservation surgery. More evidence needs to be generated to support the oncological safety and improved aesthetic outcome. Prospective data collection will significantly contribute to the generation of stronger evidence.

Keywords: oncoplastic breast conservation surgery, oncological safety, cosmetic outcomes, therapeutic mammoplasty, recurrence, survival

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