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New developments in prosthetic arm systems

Authors Vujaklija I, Farina D, Aszmann O

Received 7 March 2016

Accepted for publication 12 May 2016

Published 7 July 2016 Volume 2016:8 Pages 31—39


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Clark Hung

Ivan Vujaklija,1 Dario Farina,1 Oskar C Aszmann2

1Institute of Neurorehabilitation Systems, Bernstein Focus Neurotechnology Göttingen, University Medical Center Göttingen, Georg-August University, Göttingen, Germany; 2Christian Doppler Laboratory for Restoration of Extremity Function, Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria

Abstract: Absence of an upper limb leads to severe impairments in everyday life, which can further influence the social and mental state. For these reasons, early developments in cosmetic and body-driven prostheses date some centuries ago, and they have been evolving ever since. Following the end of the Second World War, rapid developments in technology resulted in powered myoelectric hand prosthetics. In the years to come, these devices were common on the market, though they still suffered high user abandonment rates. The reasons for rejection were trifold – insufficient functionality of the hardware, fragile design, and cumbersome control. In the last decade, both academia and industry have reached major improvements concerning technical features of upper limb prosthetics and methods for their interfacing and control. Advanced robotic hands are offered by several vendors and research groups, with a variety of active and passive wrist options that can be articulated across several degrees of freedom. Nowadays, elbow joint designs include active solutions with different weight and power options. Control features are getting progressively more sophisticated, offering options for multiple sensor integration and multi-joint articulation. Latest developments in socket designs are capable of facilitating implantable and multiple surface electromyography sensors in both traditional and osseointegration-based systems. Novel surgical techniques in combination with modern, sophisticated hardware are enabling restoration of dexterous upper limb functionality. This article is aimed at reviewing the latest state of the upper limb prosthetic market, offering insights on the accompanying technologies and techniques. We also examine the capabilities and features of some of academia’s flagship solutions and methods.

Keywords: prosthetic, amputations, rehabilitation, hand, arm


A significant portion of the injuries treated in the emergency rooms around the globe involve upper extremities.13 The majority of them occur at home,2 during work,4,5 or when performing sports.6 Considering that almost all our everyday activities depend on manipulation by the hands, severe hand injuries can truly be devastating. Consequences of such incidents can lead to long-term disabilities, also affecting the mental and social state, with difficult reintegration in the society.7,8

The severe consequences of upper limb loss have been recognized centuries ago,9 and the ideas of artificial substitution have been since then very appealing. Transition from simple cosmetic prostheses to a more functional solution was inevitable and in high demand, resulting in the development of early body-powered and cable-driven systems. These simple devices proved themselves to be very useful and, with modern materials, are still currently in use. Approximately half of the current market of upper limb prosthetics is indeed based on cable-driven systems.10

The first pneumatic hand was developed at the beginning of the 20th century, soon followed by the first electric-powered hand. At the end of the Second World War, early concepts of myoelectric prostheses were introduced.11 These devices, which linearly translated the electrical activity of the residual muscles of the stump into the velocity of closing and opening of gripers, started to be used in research laboratories and to be sold on the market in the late 1950s. The concept of direct proportional control is still present in current commercially available systems, due to its simplicity and robustness.

By the late 1960s, pneumatic prostheses were able to drive and control several joints and grip types. However, the control was inefficient and not robust enough, requiring specific anatomical features, dexterity, and cognitive effort of the patient.12 Myoelectric systems have tried to face these issues with state-based control. Accordingly, the patient would control the prosthesis using two control sites, as in the single degree of freedom (DoF) case. When there was the need to control a different joint or grip type, a co-contraction of the muscles under the two recording sites changed the control state of the prosthesis. This quite cognitively demanding system is still dominant on the market of dexterous prosthetics, mostly due to its robustness.

Numerous studies have been conducted in the past two decades, still indicating high rejection rates of all types of upper limb prosthetic devices across a variety of users.1318 Depending on the study population, rejection rates vary from 25% to >50% for myolelectric and up to 35% for body-powered devices. However, these figures have leveled off with respect to previous periods,19,20 mainly due to modern technology. However, it is possible that the trend will eventually reverse.

Hand transplantation is an alternative to the prosthetic devices, offering functionality, superior visual appeal, and integrated sensory function.21 However, it is associated with the lifelong immunosuppressant therapy, lengthy rehabilitation, loss of grip force, and high risk of complications, leading to the possible rejection.22 These issues are then combined with very high costs.

Advances in micromachining and material design have enabled construction of versatile lightweight prosthetic hands and wrists. These market products, in combination with precise, small-sized, low-consumption electromotors, corresponded to highly actuated systems. Development of high-speed processing units with the top-end battery management and large memories in small housing propelled the research into more advanced and intuitive control systems. Greater understanding of the human neuromuscular system yielded new surgical and reconstructive techniques, which now provide access to high-quality and intuitive electromyography (EMG) sources even in high-level amputations. Socket design has also benefited from this rapid development of technology and now can offer solutions that are able to host multiple surface sensors, facilitate the use of implanted electrodes, and, in combination with surgical advancements, provide direct link with the skeletal system in the form of osseointegration. Finally, three-dimensional printing is quickly becoming a viable alternative for production of highly customizable products that are lightweight and inexpensive. Several open-source hand prosthetic projects are available for personal printing, and an ever growing number of companies are already using this method for building certain components of their own products.

Considering the latest rate of innovation in the field of prosthetics, significant increase in funding, and the number of new competitors on the market, this review aims to present the latest state of functional, myoelectrically controlled upper limb prosthetic solutions. The goal is to make a literature overview of the new developments of representative hardware, control algorithms, and interfaces from both the medical and technical perspective. Even though highly significant for prosthetic applications, solutions and research in the area of sensory feedback are beyond the scope of this review.


The current market of actuated myoelectrically controlled upper limb prosthetic devices can roughly be divided into systems that address transradial/transcarpal, transhumeral, and shoulder disabilities. Each group features specific requirements, and, in general, the options for replacement are more advanced the more distal the level of impairment is.

Transradial/transcarpal solutions

Due to the complex anatomical nature of hands and yet crucial role in object handling and manipulation, their prosthetic counterparts have undergone an important evolution and functional advances in recent years. Although simple grippers are still dominant in the market, multi-actuated hands that provide several grip types or even fully controllable individual digits and finger joints are now common (Figure 1).

Figure 1 Examples of Ottobock prosthetic hands and cosmetics (from left to right): small System Inner Hand, small MyoHand VariPlus Speed, and medium Michelangelo hand.

Some of the current common characteristics of the most promising commercial hand products – i-limb Quantum by Touch Bionics, RSL Steeper’s BeBionic v3, and Ottobock’s Michelangelo – are presented in Table 1. For the sake of putting these products into perspective, the same table lists three different, already established, products aiming at children with hand disabilities, adult long stump cases, and usual transradial users – Centri Child Myoelectric Hand, Transcarpal-Hand by Ottobock Healthcare, and Select Electric Hand by Liberating Technologies, respectively.

Table 1 Features of three already established devices aiming at children population, transcarpal and transradial cases, and three commercially available flagship prosthetic hands

From Table 1, it is evident that the increase in functionality did not significantly influence the size, the weight, and the power grasp force of prosthetic hands. Moreover, the listed products all offer certain wrist solutions, indicating an overall tendency of the market for further development of this joint. Besides the features listed, each of the hands in Table 1 is also equipped with a variety of product-specific features, mostly focusing on the different grasp types and safety measures (this is further discussed in the “Control strategies” section).

Prosthetic hand devices developed by smaller companies or research laboratories include the world’s first touch sensing hand prosthesis from Vincent Systems, Evolution 2, and DARPA founded DEKA Arm RC. Evolution 2 combines the sensory feedback information with the individually motorized digits and fully actuated thumb in a compact and light package (∼400 g).23 The DEKA Arm RC is the heaviest of the products so far listed (1,270 g)24 and, in its third generation, offers highly actuated digits and thumb with an included compound wrist that can be actuated in three DoFs.25

In order to provide a more natural object manipulation and therefore increase functional benefits to the users,26 modern prosthetic hand devices are frequently accompanied by an actively or passively controllable wrist joint. Passive versions of prosthetic wrists can be manually adjusted by the user in order to be in either compliant mode or to lock in one of the predefined positions in flexion/extension direction (Ottobock AxonWrist, Touch Bionics Flexion Wrist, BeBionic FlexionWrist) or along the rotation axis (Ottobock AxonRotation, Touch Bionics QWD, BeBionic Short Wrist). Additionally, certain vendors offer wrists that allow prosthetic hands to be positioned in any direction (MyolinoWrist 2000, BeBionic Multi-Flex). Commercial active units are almost exclusively focused on the wrist rotation (MC Wrist Rotator, Ottobock Electric Wrist Rotator).

Transhumeral and shoulder disarticulation solutions

The more proximal the upper limb impairment is, the greater the disability. In transhumeral amputations, the absence of an elbow requires an additional prosthetic joint to substitute the missing two DoFs. Even though the rotation of the forearm can be compensated using the wrist rotation unit, the major setback at this level of disability is the reduced number of sources and methods for controlling all the necessary prosthetic components. As for the wrist, prosthetic elbows can be passive or active with several locking positions. Passive or body-powered elbows are dominant on the market, though several major vendors also provide electrically powered, myoelectrically controllable devices. Some representative products and their characteristics are listed in Table 2. The DEKA Arm HC offers a motorized elbow solution with a limited range of motion to prevent reaching the face for safety reasons.25 This characteristics and the absence of the free swing mode have not been well received by the users.25

Table 2 Features of commercially available myoelectric elbows

Even though improvements in academia have indicated possible solutions in designing elbow joints with anthromorphic characteristics,27 one of the current main challenges is the design of a device fully compliant with all the standards and yet light enough to be suited for children and frail adults.

Powered shoulder joints are more complex and currently not present on the market. Nonetheless, promising solutions have been presented in research laboratories.25,28 The DEKA arm HC has recently received Food and Drug Administration approval,29 and it offers four movement directions in the shoulder joint.25 Moreover, for exploring the full possibilities of the targeted muscle reinnervation (TMR) approach, a modification of the LTI-Collier shoulder joint has been developed with an added electronic lock/unlock feature.28

Socket technology

The amount of time a user wears a prosthesis mainly depends on the socket fit and its design.30 Inadequate prosthetic fit might lead to limited range of motion, discomfort, and general poor performance,31 usually resulting in the abandonment of the device.32

After the development of the Otto Bock Muenster style socket in the 1960s33 and the Northwestern University socket in 1972,34 the transradial powered prosthesis socket design has not significantly changed. The introduction of flexible thermoplastics has indeed been the only major improvement.35 At the end of 1990s, silicon liners have been introduced, and the transparent, moldable plastics allowed better analysis of the inside socket dynamics, resulting in a tighter contouring around the fitted stump30 (Figure 2). Nowadays, new textile materials allow better, more hygienic, and less obstructing harnesses to be developed and custom fit to higher level upper limb amputees. The general tendency over the past few years, which was enabled through these novel materials, is the design of anatomically contoured sockets for all levels of amputation.36

Figure 2 Example socket design with custom pattern, silicon liner, and Ottobock Energy Pack housing.

Based on the osseointegration technique introduced ∼60 years ago,37 an advanced mounting concept of the upper limb prosthesis has been developed and applied.38 The main idea behind this technique is to exploit the direct structural and functional connection between the skeletal bone and the surface of the titanium implant,39 which would further be connected to an additional implant penetrating the skin.40 In this way, a point for a direct, rigid connection of the prosthesis and the skeletal system is created.41 Osseointegration offers numerous advantages over the traditional sockets by providing a more intimate fit, increased range of motion, and osseoperception.42,43 However, it also requires additional surgery and poses potential risks of infection, implant fracture, or incomplete integration requiring revision surgeries.44,45

The introduction of implantable sensing technologies for EMG detection and control of prosthetic devices such as implantable myoelectric sensor46 requires certain revisions of the standard sockets. Namely, implantable myoelectric sensor compatible shafts are equipped with transmitter/receiver coil capable of enclosing the stump and receiving the signal transmitted by the implanted EMG electrodes.47

Other, more research-oriented, invasive solutions, such as implantable electrode arrays,48 fine wire-based systems,49 and epimysial electrodes,50 are at a prototype stage. Nerve interfacing solutions51 for efferent decoding remain currently highly complex without sufficient benefits.

Control strategies

Myoelectric prosthetic upper limbs have been known for over half a century.11 As previously elaborated, advances have been made in many aspects of these devices. Yet, the commercially available control systems up until recently have practically remained unchanged. The initial two-channel control allowing direct proportional steering of a single DoF has been extended to sequentially drivable multiple DoFs using a state machine approach.52 With this approach, the user can decide which DoF of the device to control by cycling through states using co-contractions or by quickly repeating a specific muscle activation pattern.53,54 For example, Michelangelo hand users may switch between DoFs by modulating the contraction speed.54 Regardless, all these approaches, even though quite robust, are unintuitive and cumbersome especially in the high-level amputation cases, which require articulation of numerous DoFs.55

Some prosthetic hand vendors proposed a decrease in the direct control by the user, with the introduction of supportive technologies. For example, BeBionic v3 has a plain switch for alternating between groups of preset grip types.56 Touch Bionics offers i-mo technology (Touch Bionics Inc., Livingston, UK) that utilizes gyroscopes in order to detect sudden, user-elicited direction changes of the device that is used to select preset gestures.57 Moreover, users of modern prosthetics are now given access to applications that can run on external devices capable of fine tuning and setting up gestures or gesture patterns.56,58,59 This allows high-level customization. Touch Bionics even proposed the exchange of control settings through QR codes.60 Finally, the same company introduced the so-called “grip chips” that can automatically preshape the hand once the prosthetic finds itself in the close proximity of one of these devices. Chips can then be placed in the characteristic spots within the user’s everyday environment.61 Even though promising, all these novel features are yet to be clinically tested and their impact on the improvement of the quality of life remains to be demonstrated.

Academia has been extensively working on numerous prosthetic control solutions in the form of machine-learning approaches that are mostly based on the assumption that distinguishable and repeatable signal patterns exist among different motor tasks.62,63 There are several classification schemes proposed in the past several decades. However, the transition from the laboratory tests to the clinical and everyday practice has been very challenging. Only recently, a first pattern recognition-based system, COAPT,64 has become commercially available, but it is yet to be seen how well this system will be accepted in the market.

The main issue of EMG pattern recognition-based systems is that they rely on repeatable matching of the produced EMG patterns during prosthetic manipulation to those used for system training. On the other hand, these patterns tend to significantly change due to environmental factors such as sweat or electrode shift, as well as fatigue, load, limb position, or simply due to the user’s change of focus.6569 Another drawback of these solutions is their limited ability to successfully cope with simultaneous motions, which makes them still not fully intuitive and somewhat cognitively demanding.70

In order to overcome some of these issues, a new direction in myoelectric control research has been taken and biologically inspired algorithms have been designed. They combine techniques of mathematical regression with physiologically based models that allow intuitive control.71,72 These systems may enable the users to intuitively control multiple DoFs in a simultaneous and proportional way.73,74 These techniques have shown promising potential, though they are limited in the number of DoFs that can be controlled, at least without relying on nonintuitive motions and high-density EMG recordings.75

Recently, a system that combines signal classification and regression for the control of the hand and wrist, respectively, has been proposed,76 although full clinical testing is still lacking.77

Surgical techniques for improved prosthetic experience

The importance of a proper stump management has been recognized long time ago, and its influence on prosthetic fitting, control, and acceptance can be significant.78 Various surgical techniques have been used for salvation or restoration of the affected hand and arm function, thus enabling simpler and more efficient prosthetic solutions. Among others, these surgical methods include surgical tendon transfers,79,80 a variety of flaps,8184 digit and toe transfers,8587 and skin grafting.88,89

Mastering of the aforementioned techniques and broadening of the knowledge about nerve transfers in the past decade led to the development of TMR that transfers residual nerves that have lost their original targeted muscles to alternative muscle sites.90 By treating muscles as biological amplifiers of the signals transmitted through nerves,91 TMR allows reformation of several well-separated sources of intuitive EMG signals, which can be of high value for prosthetic control.92 The Ottobock DynamicArm Plus in combination with the MyoHand Vari PlusSpeed terminal device accompanied by Wrist Rotator and a custom TMR socket enables the control of up to six DoFs following successful TMR procedure. To our knowledge, this is currently the only strictly TMR dedicated commercially available prosthetic solution on the market.

Recently, the concept of bionic reconstruction has been proposed for various scenarios after hand/arm trauma, extending the reconstructive options beyond the biological scope. In patients suffering from severe brachial plexus injuries presenting permanent hand dysfunction, which is beyond restoration using usual biological means alone, bionic reconstruction can offer a valid solution for restoring hand use where even the simplest of the aforementioned terminal devices are now allowing them to have better quality of life.93 The success of this technique depends on numerous factors. One of the crucial aspects is the neurorehabilitation program that is delivered to the patients throughout the procedure.


By observing the current state of the upper limb prosthetic market, the most rapid development occurred during the last decade as the result of advances in technology, surgical techniques, and increased knowledge of human anatomy and physiology.

We have presented some of the latest prosthetic solutions on the market and have given insights in what academia is able to offer in the upcoming period. These systems offer numerous features when equipped with the state-of-the-art technology. Nowadays, prosthetic hands closely resemble the anatomical dimensions of their biological counterparts, while the solutions for higher level impairments are yet to match these specifications. Prosthetic solutions replacing certain DoFs, such as shoulder movements, are still missing.

The introduction of modern materials has allowed better and more intimate socket design that enables improved prosthetic experience for the users. This facilitated development of new socket fitting techniques allow orthopedic technicians to custom-match the residual limb anatomy of each user. Advances in implant design have come to a point where prosthetic fitting through osseointegration is a viable option. This kind of interface, directly coupled to the user’s skeletal system, provides increased range of motion and osseoperception. Following the advances of implantable sensor technologies, the new socket designs include features harvesting the significant potential of such solutions through embedded transmitter/receiver coils.

In order to improve the functional potential of upper limb-impaired patients, new surgical techniques have been recently proposed. TMR and bionic reconstruction, for example, provide important functional benefits to the user, in particular for high-level amputees and patients with brachial plexus injuries.

The current bottleneck of the upper limb prosthetic development seems to be the control of the robotic limbs. The majority of commercially available devices are still relying on the cumbersome mode-switching approaches dating some decades ago, while novel techniques seem to continuously fail in making a stable transition into the market. There are new solutions that have recently emerged but that have not yet been tested clinically on a large scale.

High prosthetic abandonment rates are still present, though they have been stagnating compared to the trends from about two decades ago. This can be attributed to the significant improvement in robustness and hardware design. Nevertheless, in order for these figures to start dropping, advances are still needed in prosthetic control, general system simplification, and custom, user-oriented solutions.


This work was supported by the Christian Doppler Research Foundation of the Austrian Federal Ministry of Science, Research and Economy and by the European Research Council Advanced Grant DEMOVE (contract #267888).


The authors report no conflicts of interest in this work.



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