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Negative and positive self-thoughts predict subjective quality of life in people with schizophrenia

Authors Takeda T, Nakataki M, Ohta M, Hamatani S, Matsuura K, Yoshida R, Kameoka N, Tominaga T, Umehara H, Kinoshita M, Watanabe S, Numata S, Sumitani S, Ohmori T

Received 15 October 2018

Accepted for publication 19 December 2018

Published 21 January 2019 Volume 2019:15 Pages 293—301


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Taro Kishi

Tomoya Takeda,1 Masahito Nakataki,2 Masashi Ohta,2 Sayo Hamatani,3 Kanae Matsuura,2 Reona Yoshida,2 Naomi Kameoka,2 Takeo Tominaga,4 Hidehiro Umehara,2 Makoto Kinoshita,2 Shinya Watanabe,4 Shusuke Numata,4 Satsuki Sumitani,5 Tetsuro Ohmori4

1Graduate School of Medical Science, Tokushima University, Tokushima, Japan; 2Department of Psychiatry, Tokushima University Hospital, Tokushima, Japan; 3Research Center for Child Mental Development, Chiba University, Chiba, Japan; 4Department of Psychiatry, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; 5Academic Support Office for Students with Special Needs, Tokushima University, Tokushima, Japan

Purpose: Recently, cognitive variables such as negative and positive self-belief and thoughts have attracted much attention because they are associated with functional outcomes and quality of life (QOL). However, it is unclear how cognitive variables affect subjective and objective QOL. This study aimed to investigate the relationship of negative and positive self-belief and thoughts with subjective and objective QOL.
Participants and methods: Thirty-six people with schizophrenia participated in this study. Subjective and objective QOL were assessed with the Schizophrenia Quality of Life Scale (SQLS) and Quality of Life Scale (QLS), respectively. Neurocognitive function was assessed with the Brief Assessment of Cognition in Schizophrenia (BACS). Clinical symptoms were assessed with the Positive and Negative Syndrome Scale and Calgary Depression Scale for Schizophrenia. Side effects were assessed with the Drug-induced Extrapyramidal Symptoms Scale (DIEPSS). Negative and positive self-belief and thoughts were assessed with the Defeatist Performance Belief Scale and Automatic Thoughts Questionnaire-Revised. A generalized linear model was tested, with subjective and objective QOL as the response variable and symptoms, neurocognitive function, and cognitive variables that were significantly correlated with subjective and objective QOL as explanatory variables.
Results: In the schizophrenia group, the common objects score on the QLS was predicted by the composite BACS score, and the total QLS score was predicted by the DIEPSS score. Motivation and Energy, Psychosocial, and Symptoms and Side effects scores on the SQLS were predicted by depression and by negative automatic thought (NAT) and positive automatic thought (PAT).
Conclusion: Our results indicated that key targets for improving objective and subjective QOL in people with schizophrenia are side effects, neurocognitive function, depression, and NAT and PAT.

Keywords: defeatist performance belief, negative and positive automatic thoughts, subjective quality of life, objective quality of life, schizophrenia

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