Back to Journals » International Journal of Nanomedicine » Volume 6

Multi-access drug delivery network and stability

Authors Mitatha S, Moongfangklang N, Jalil MA, Suwanpayak N, Ali J, Yupapin PP

Published 23 August 2011 Volume 2011:6 Pages 1757—1764

DOI https://doi.org/10.2147/IJN.S23861

Review by Single-blind

Peer reviewer comments 5

S Mitatha1, N Moongfangklang1, MA Jalil2, N Suwanpayak3, J Ali4, PP Yupapin3
1
Hybrid Computing Research Laboratory, Faculty of Engineering, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand; 2Ibnu Sina Institute of Fundamental Science Studies, Nanotechnology Research Alliance, Universiti Teknologi Malaysia, Johor Bahru, Malaysia; 2King Mongkut’s Institute of Technology Ladkrabang, Chumphon Campus, Chumphon, Thailand; 3Nanoscale Science and Engineering Research Alliance (N’SERA), Advanced Research Center for Photonics, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand; 4Institute of Advanced Photonics Science, Nanotechnology Research Alliance, Universiti Teknologi Malaysia, Johor Bahru, Malaysia

Abstract: A novel design of a multi-drug delivery network and diagnosis using a molecular network is proposed. By using a pair of tweezers to generate the intense optical vortices within the PANDA ring resonator, the required molecules (drug volumes) can be trapped and moved dynamically within the molecular bus networks, in which the required drug delivery targets can be achieved within the network. The advantage of the proposed system is that the diagnostic method can be used within a tiny system (thin film device or circuit), which is available as an embedded device for diagnostic use in patients. In practice, the large molecular networks such as ring, star, and bus networks can be integrated to form a large drug delivery system. The channel spacing of the trapped volumes (molecules) within the bus molecular networks can be provided by using the appropriate free spectrum range, which is analyzed and discussed in the terms of crosstalk effects. In this work, crosstalk effects of about 0.1% are noted, which can be neglected and does not affect the network stability.

Keywords: drug delivery network, molecular networks, molecular diagnosis, neural system and network

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other articles by this author:

Corrigendum

Jalil MA, Moongfangklang M, Innate K, Mitatha S, Ali J, Yupapin PP

International Journal of Nanomedicine 2012, 7:3279-3280

Published Date: 29 June 2012

Acoustic cardiac signals analysis: a Kalman filter–based approach

Salleh SH, Hussain HS, Swee TT, Ting CM, Noor AM, Pipatsart S, Ali J, Yupapin PP

International Journal of Nanomedicine 2012, 7:2873-2881

Published Date: 11 June 2012

Generation of THz frequency using PANDA ring resonator for THz imaging

Jalil MA, Abdolkarim A, Saktioto T, Ong CT, Yupapin PP

International Journal of Nanomedicine 2012, 7:773-779

Published Date: 15 February 2012

Gold nanoparticle trapping and delivery for therapeutic applications

Aziz MS, Suwanpayak N, Jalil MA, Jomtarak R, Saktioto T, Ali J, Yupapin PP

International Journal of Nanomedicine 2012, 7:11-17

Published Date: 29 December 2011

Human facial neural activities and gesture recognition for machine-interfacing applications

Hamedi M, Salleh SH, Tan TS, Ismail K, Ali J, Dee-Uam C, Pavaganun C, Yupapin PP

International Journal of Nanomedicine 2011, 6:3461-3472

Published Date: 16 December 2011

Embedded nanomicro syringe on chip for molecular therapy

Jalil MA, Suwanpayak N, Kulsirirat K, Suttirak S, Ali J, Yupapin PP

International Journal of Nanomedicine 2011, 6:2925-2932

Published Date: 18 November 2011

Molecular network topology and reliability for multipurpose diagnosis

Jalil MA, Moongfangklang N, Innate K, Mitatha S, Ali J, Yupapin PP

International Journal of Nanomedicine 2011, 6:2385-2392

Published Date: 19 October 2011

Heart detection and diagnosis based on ECG and EPCG relationships

Phanphaisarn W, Roeksabutr A, Wardkein P, Koseeyaporn J, Yupapin PP

Medical Devices: Evidence and Research 2011, 4:133-144

Published Date: 26 August 2011

Proposal for Alzheimer’s diagnosis using molecular buffer and bus network

Mitatha S, Moongfangklang N, Jalil MA, Suwanpayak N, Saktioto T, Ali J, Yupapin PP

International Journal of Nanomedicine 2011, 6:1209-1216

Published Date: 14 June 2011

Blood cleaner on-chip design for artificial human kidney manipulation

Suwanpayak N, Jalil MA, Aziz MS, Ismail FD, Ali J, Yupapin PP

International Journal of Nanomedicine 2011, 6:957-964

Published Date: 2 May 2011

Molecular buffer using a PANDA ring resonator for drug delivery use

N Suwanpayak, MA Jalil, MS Aziz, et al

International Journal of Nanomedicine 2011, 6:575-580

Published Date: 22 March 2011

Readers of this article also read:

Molecular targets in arthritis and recent trends in nanotherapy

Roy K, Kanwar RK, Kanwar JR

International Journal of Nanomedicine 2015, 10:5407-5420

Published Date: 26 August 2015

Is increasing the dose of Entecavir effective in partial virological responders?

Erturk A, Adnan Akdogan R, Parlak E, Cure E, Cumhur Cure M, Ozturk C

Drug Design, Development and Therapy 2014, 8:621-625

Published Date: 29 May 2014

Photodynamic therapy of a 2-methoxyestradiol tumor-targeting drug delivery system mediated by Asn-Gly-Arg in breast cancer

Shi J, Wang Z, Wang L, Wang H, Li L, Yu X, Zhang J, Ma R, Zhang Z

International Journal of Nanomedicine 2013, 8:1551-1562

Published Date: 19 April 2013

Controlled-release approaches towards the chemotherapy of tuberculosis

Saifullah B, Hussein MZ, Hussein Al Ali SH

International Journal of Nanomedicine 2012, 7:5451-5463

Published Date: 12 October 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010