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Transplant Research and Risk Management

ISSN: 1179-1616

Professor Qing Yi

Professor Yi

Center for Translational Research in Hematologic Malignancies, Houston Methodist Cancer Center, Houston Methodist Research Institute, Houston, TX, USA

Dr. Qing Yi, MD, PhD, is one of the leading investigators in the field of immune regulation and immunotherapy in multiple myeloma. He has been working on characterizing myeloma-specific T cells and their subsets, and examining their functions in relationship to myeloma tumor cells in both in vitro and in vivo experiments, and on identifying novel myeloma-associated antigens for immunotherapy. In addition, Dr. Yi has been conducting clinical trials to evaluate the efficacy of immunizing patients with idiotype or dendritic cell-based vaccines. His research will continue focusing on the development of effective immunotherapy strategies to cure myeloma patients in combination with high-dose chemotherapy.

Recently, Dr. Yi and his group discovered that anti-β2-microglublin antibodies could kill myeloma cells. His research team is thus examining whether these antibodies have therapeutic potentials to treat patients with myeloma. Furthermore, his recent studies demonstrate that C-reactive protein (CRP) protects myeloma cells from chemotherapy drug-induced apoptosis, and further work is under way to explore whether CRP can be targeted for myeloma therapy. Dr. Yi's research has been supported by US federal and foundation grants since 1998, and he has authored over 120 papers in the fields of myeloma research, immunotherapy of cancer, and tumor biology.

Editorial Board

Gurvinder Kaur Ph.D. Associate Professor, Department of Medical Education (DOME), Texas Tech University Health Sciences Center, Texas, USA

Camillo Ricordi, MD, FNAI, Stacy Joy Goodman Professor of Surgery and Chief, Division of Cellular Transplantation, Distinguished Professor of Medicine, Professor of Biomedical Engineering, Microbiology and Immunology, Director, Diabetes Research Institute and Cell Transplant Center, University of Miami, Fellow, National Academy of Inventors, USA.