Back to Journals » Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy » Volume 1

Insulin autoimmune syndrome in a patient with ANCA-associated glomerulonephritis

Authors Ka T, Moriwaki Y, Nakanishi T, Yamamoto T

Published 19 June 2008 Volume 2008:1 Pages 1—2


Review by Single-blind

Peer reviewer comments 1

Tsuneyoshi Ka1, Yuji Moriwaki1, Takeshi Nakanishi2, Tetsuya Yamamoto1

Divisions of 1Endocrinology and Metabolism, and 2Kidney and Dialysis, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan

Abstract: The patient, a 66-year-old woman, who has been under hemodialysis due to antineutrophil cytoplasm autoantibody (ANCA)-associated glomerulonephritis since 2003, was hospitalized because of cold sweating, general fatigue, and somnolence. Hypoglycemia (43 mg/dL) with markedly elevated insulin level (1410 µU/mL) and insulin antibody was found in her serum. She was diagnosed as having insulin autoimmune syndrome. She has not taken any medication that might cause insulin autoimmune syndrome. The possible association of ANCA-associated glomerulonephritis with insulin autoimmune syndrome is discussed.

Keywords: hypoglycemia, insulin antibody, ANCA, insulin autoimmune syndrome

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]