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Incidence and Risk Factors of Emergence Delirium after Anesthesia in Elderly Patients at a Postanesthesia Care Unit in Ethiopia: Prospective Observational Study

Authors Assefa MT, Chekol WB, Melesse DY, Nigatu YA

Received 22 December 2020

Accepted for publication 28 January 2021

Published 9 February 2021 Volume 2021:12 Pages 23—32

DOI https://doi.org/10.2147/PROM.S297871

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Lynne Nemeth


Muleta Teshome Assefa, Wubie Birlie Chekol, Debas Yaregal Melesse, Yonas Addisu Nigatu

Department of Anesthesia, College of Medicine and Health Sciences, University of Gondar, Gondar, Northwest Ethiopia, Ethiopia

Correspondence: Wubie Birlie Chekol Email birliewubie@gmail.com

Introduction: Emergence delirium is a common incidental trouble in elderly patients that may interfere with patient recovery and will challenge the attending staff. So, we aimed to determine the incidence and risk factors of emergence delirium after anesthesia in elderly patients at the University of Gondar Comprehensive Specialized Hospital (UOGCSH), Post Anesthesia Care Unit (PACU).
Methods: A prospective observational study was conducted from February 20 to May 20, 2020 among elective and emergency procedures in patients aged 60 years and over at UOGCSH, PACU. Data were analyzed by SPSS version 20. The association between outcome variables and independent variables was determined by binary logistic regression analysis. The strength of association of variables was determined by calculating crude and adjusted odds ratio with 95%CI. A P-value of < 0.05 was used to determine the significance of the variable.
Results: A total of 172 patients were included with a 97.7% response rate. The incidence of emergence delirium at PACU was 40.7% (95%CI: 32– 48). Perioperative intravenous narcotic used (AOR: 5.1, 95%CI: 1.265– 20.565), intraoperative excessive blood loss (AOR: 6.5, 95%CI: 2.47– 17.02), and preoperative anxiety (AOR: 7, 95%CI: 1.757– 28.549) were significantly associated with emergence delirium.
Conclusion: Perioperative intravenous narcotic, intraoperative blood loss, and preoperative anxiety were significantly associated with emergence delirium. Reassuring patients preoperatively, giving full information about anesthesia and adequate postoperative pain management may decrease the magnitude of emergence delirium.

Keywords: delirium, emergence delirium, incidence and associated factors, postanesthesia care

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