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Hepatopulmonary syndrome after radiofrequency ablation of recurrent intrahepatic cholangiocarcinoma: a case report

Authors Wang Y, Ma K, Zhong A, Xiong Q, Chen J

Received 16 April 2015

Accepted for publication 25 June 2015

Published 2 April 2019 Volume 2019:12 Pages 2431—2438

DOI https://doi.org/10.2147/OTT.S86702

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Jianmin Xu


Yu Wang, Kuansheng Ma, Ai Zhong, Qing Xiong, Jian Chen

Institute of Hepatobiliary Surgery, Southwestern Hospital, People’s Liberation Army Third Military Medical University, Chongqing, People’s Republic of China

Background: Radiofrequency ablation (RFA) is one of the definitive treatment modalities for liver cancer and has been increasingly used in the scenario of small-sized liver cancer. It is generally believed that RFA is minimally invasive and associated with a favorable safety profile in liver cancer patients. However, this interventional technique is subject to some morbidity in high-risk patients, such as those with complicating cirrhosis or a liver cancer located at a refractory segment.
Methods: Herein, we report the case of a middle-aged woman who developed acute liver failure with a complicating respiratory failure after RFA of recurrent intrahepatic cholangio­carcinoma.
Results: A diagnosis of hepatopulmonary syndrome was established. The patient was hospitalized in the intensive care unit for mechanical ventilation. Finally, the patient recovered from an eventful clinical course and survived free of recurrence until the last follow-up visit at 1 year after the discharge.
Conclusion: Our case report warns that hepatopulmonary syndrome, a less common morbidity secondary to liver cancer RFA, should require timely identification and appropriate management due to its life-threatening outcome.

Keywords: liver cancer, radiofrequency ablation, acute liver failure, hepatorenal syndrome, intensive care

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