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Health-related quality of life in patients with iron deficiency anemia: impact of treatment with intravenous iron

Authors Strauss WE, Auerbach M

Received 29 March 2018

Accepted for publication 8 June 2018

Published 27 August 2018 Volume 2018:9 Pages 285—298

DOI https://doi.org/10.2147/PROM.S169653

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 3

Editor who approved publication: Professor Lynne Nemeth


William E Strauss,1 Michael Auerbach2

1AMAG Pharmaceuticals, Inc., Waltham, MA, USA; 2Auerbach Hematology and Oncology, Baltimore, MD, USA

Abstract: Most physicians appear to be aware of the health consequences of advanced anemia, especially in the acute setting, frequently responding with a not inconsequential therapeutic default of transfusion. In contrast, the profound impact that chronic anemia, of any degree, may have on a patient’s performance is underappreciated. The focus of this review is to 1) delineate the consistent and broad impact of anemia on patient quality of life as documented by multiple well-validated patient-reported outcome instruments and 2) demonstrate the essential normalization of the debilitation as assessed by these instruments following the administration of intravenous iron.

Keywords: anemia, health-related quality of life, intravenous iron, iron deficiency anemia

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