Back to Journals » Vascular Health and Risk Management » Volume 13

Focusing on a complete blood cell parameter: mean platelet volume levels may be a predictor of coronary slow flow

Authors Yılmaz M, Dağlı MN, Uku Ö, Bilen MN, Korkmaz H, Erdem K, Kurtoğlu E

Received 29 October 2016

Accepted for publication 24 March 2017

Published 7 July 2017 Volume 2017:13 Pages 255—261

DOI https://doi.org/10.2147/VHRM.S126105

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 3

Editor who approved publication: Professor Daniel Duprez


Mücahid Yılmaz,1 Mustafa Necati Dağlı,2 Ökkeş Uku,1 Mehmet Nail Bilen,1 Hasan Korkmaz,2 Kenan Erdem,3 Ertuğrul Kurtoğlu1

1Department of Cardiology, Elazığ Education and Research Hospital, 2Department of Cardiology, FIRAT University School of Medicine, Elazığ, 3Department of Cardiology, Sivas Hospital State, Sivas, Turkey

Background: The relationship between increased mean platelet volume (MPV) and atherosclerosis is well known. In the present study, MPV in patients with coronary slow flow (CSF) and in cases with normal coronary anatomy (NCA) was investigated and compared with the aim of identifying the relationship between CSF and MPV.
Patients and methods:
We studied 40 patients previously determined via coronary angiography as having NCA and 40 patients with CSF in the coronary blood stream, as identified by thrombolysis in myocardial infarction square. Thus, a total of 80 patients from the Elaziğ Education and Research Hospital (Elaziğ, Turkey) were included in the present study retrospectively and laboratory and anamnesis information was scanned into their files. The relationship between MPV and CSF was studied.
Results: MPV levels were observed to be significantly higher in the CSF group compared to the NCA group (10.05±1.3 and 8.6±0.6, p<0.001). In receiver operating characteristics analyses, it was determined that an MPV >9.05 measured in CSF patients at application had a predictive specificity of 77.5% and sensitivity of 77.5% for CSF (area under the curve: 0.825, 95% confidence interval [CI]: 0.726–0.924, p<0.0001). It was found that MPV level was an independent predictor of CSF (β=−600, p<0.001, 95% CI: −0.383 to −0.176).
Conclusion: MPV is increased in patients with CSF when compared to patients with NCA. This finding supports the fact that MPV could be a predictor of CSF.

Keywords: coronary slow flow, mean platelet volume, atherosclerosis

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]