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Epidemiological evaluation of YAG capsulotomy incidence for posterior capsule opacification in various intraocular lenses in Japanese eyes

Authors Nishi Y, Ikeda T, Nishi K, Mimura O

Received 5 June 2015

Accepted for publication 14 July 2015

Published 1 September 2015 Volume 2015:9 Pages 1613—1617

DOI https://doi.org/10.2147/OPTH.S89966

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Yang Liu

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Yutaro Nishi,1,2 Tomohiro Ikeda,1 Kayo Nishi,2 Osamu Mimura1

1Department of Ophthalmology, Hyogo College of Medicine, Hyogo, 2Nishi Eye Hospital, Osaka, Japan

Background and objective: We investigated the yttrium aluminum garnet (YAG) capsulotomy rates in various intraocular lenses (IOLs).
Study design/patients and methods: We retrospectively analyzed 23,440 eyes implanted with either MA60BM, MA60AC, VA-60BB, CeeOnEdge, Clariflex, Technis Z9002, SI-40NB, or UV26T IOLs. We calculated the YAG capsulotomy rates at 1, 3, 5, and 10 years post lens implantation.
Results: YAG capsulotomy rates at 3 years postimplantation for the eight groups of IOLs were, respectively, 3.7%, 3.9%, 23.7%, 3.4%, 4.5%, 4.7%, 10.4%, and 21.0%. YAG capsulotomy rates at 10 years postimplantation for the MA60BM and SI-40NB IOLs were, respectively, 9.1% and 15% (P<0.05). The average YAG rates for all sharp-edged and round-edged IOLs at 5 years postimplantation were, respectively, 5.2%±0.7% and 25.6%±9.0% (P<0.05).
Conclusion: In all studied IOLs, posterior capsule opacification prevention seemed to be associated with the posterior optic sharp-edge design. Round-edged silicone IOLs may also retard posterior capsule opacification formation, though not as much as sharp-edged IOLs. As the follow-up period progressed, round-edged silicone IOLs showed significantly higher YAG rates than sharp-edged IOLs.

Keywords: silicone, intraocular lenses, sharp optic edge, chi-square test, implantation surgery, posterior capsule opacification

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