Back to Journals » Pediatric Health, Medicine and Therapeutics » Volume 2

Endocrine causes of systemic hypertension in children and adolescents: a clinical review

Authors Kamboj, Gupta, Torres, Patel D

Published 28 April 2011 Volume 2011:2 Pages 39—47

DOI https://doi.org/10.2147/PHMT.S15789

Review by Single-blind

Peer reviewer comments 3


Manmohan Kamboj1, Vibha Gupta2, Alfonso Torres2, Dilip R Patel2
1Nationwide Children's Hospital, Columbus, OH, USA; 2Michigan State University, Kalamazoo Center for Medical Studies, Kalamazoo, MI, USA

Abstract: Hypertension has been well recognized as a major contributor of chronic cardiovascular disease, resulting in significant morbidity and mortality not only in adults but also in children and adolescents. Primary or essential hypertension refers to cases where no underlying etiology is apparent for the high blood pressure, and accounts for a majority of the patients. Secondary hypertension refers to a much smaller group of patients in whom the blood pressure elevation may be attributed to an underlying cause. With improved diagnostic techniques, some cases of previously diagnosed essential hypertension may be found to have an underlying etiology. Endocrine causes account for a relatively small proportion of all patients with hypertension. In the following discussion, only secondary hypertension due to endocrine-related causes will be discussed.

Keywords: primary hyperalsosteronism, paraganglioma, beta-hydroxy-steroid dehydogenase deficiency, Liddle syndrome, Gordon syndrome

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]