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Does roflumilast induce phagocytic activity in COPD patients?

Authors Ghosh B, Vanjare NV

Received 21 July 2015

Accepted for publication 24 July 2015

Published 11 September 2015 Volume 2015:10(1) Pages 1931—1934

DOI https://doi.org/10.2147/COPD.S92812

Checked for plagiarism Yes

Editor who approved publication: Dr Richard Russell

Baishakhi Ghosh,1,2 Nitin V Vanjare1

1Chest Research Foundation (CRF), Pune, Maharashtra, India; 2Faculty of Health and Biomedical Science (FOHBS), Symbiosis International University, Pune, Maharashtra, India

We read the article by Porpodis et al1 with great interest. In this study, the authors have evaluated the effect of roflumilast on the phagocytic activity of systemic phagocytes in severe and very severe COPD patients by measuring the oxidative burst post-bacterial stimulation. The study group for this study involved 21 severe or very severe COPD patients who were administered roflumilast in addition to other COPD treatments such as long-acting beta-adrenoceptor agonists (LABA) + inhaled corticosteroids (ICS) + long-acting anti-muscarinic agent (LAMA) or ICS + LABA.

View original paper by Porpodis and colleagues.

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