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Demodex blepharitis: clinical perspectives

Authors Fromstein SR, Harthan JS, Patel J, Opitz DL

Received 30 January 2018

Accepted for publication 17 April 2018

Published 4 July 2018 Volume 2018:10 Pages 57—63

DOI https://doi.org/10.2147/OPTO.S142708

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Ms Justinn Cochran

Peer reviewer comments 2

Editor who approved publication: Mr Simon Berry


Stephanie R Fromstein, Jennifer S Harthan, Jaymeni Patel, Dominick L Opitz

Department of Clinical Education, Illinois College of Optometry, Chicago, IL, USA

Abstract: Demodex folliculorum and Demodex brevis are two mites which infest the human eye and which may, in excess, lead to a wide range of anterior segment findings. Demodex mites have been implicated in anterior and posterior blepharitis, blepharoconjunctivitis, blepharokeratitis, and beyond. Due to significant overlap with other anterior segment conditions, Demodex infestation remains underdiagnosed and undertreated. Definitive diagnosis can be made with lash sampling, and the most common mode of treatment is with tea tree oil in varying concentrations. This article summarizes elements of pathogenesis, diagnosis, and management critical to clinical care of this common condition.

Keywords: Demodex folliculorum, Demodex brevis, blepharitis, blepharoconjunctivitis, meibomian gland dysfunction, ocular rosacea

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