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Correlation of Clinical Features, Laboratory Finding, and Pelvic Ultrasonography of Pulmonary Tuberculosis Women with Infertility

Authors Madjid TH, Ardhi I, Permadi W, Susiarno H, Krisnadi SR, Wirakusumah FF, Parwati I

Received 23 August 2019

Accepted for publication 15 November 2019

Published 31 December 2019 Volume 2019:12 Pages 485—489


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser

Video abstract presented by Tita Husnitawati Madjid.

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Tita Husnitawati Madjid,1 Iqbal Ardhi,1 Wiryawan Permadi,1 Hadi Susiarno,1 Sofie Rifayani Krisnadi,1 Firman Fuad Wirakusumah,1 Ida Parwati2

1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin Hospital, Bandung, Indonesia; 2Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin Hospital, Bandung, Indonesia

Correspondence: Tita Husnitawati Madjid
Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin Hospital, Jl Pasteur No. 38, Bandung, Jawa Barat 40161, Indonesia
Tel +6222 203 2530
Fax +6222 203 9086

Background and purpose: The prevalence of tuberculosis (TB) in Indonesia is still high, whereas the prevalence of extra pulmonary tuberculosis such as female genital tuberculosis (FGTB) affecting infertility is unknown. FGTB caused irreversible severe damaged of tubes and endometrium, resulting in tubal occlusion and partial or total obliteration of the uterine cavity. Diagnosis of FGTB is difficult. Therefore, a prompt diagnosis and treatment of pulmonary TB in women can prevent fertility complications. This study aims to analyze the correlation of clinical features taken from the history, physical examination, investigation of blood laboratory and gynecological ultrasound of pulmonary tuberculosis women with infertility.
Patients and methods: This was an observational analytic study with cross-sectional method. Subjects were women with pulmonary TB treated in TB-DOTS (tuberculosis-directly observed treatment, short-course) services at Dr Hasan Sadikin Hospital Bandung during December 2016 until March 2017. Subjects were divided into two groups consist of 32 TB patients with infertility, and 35 TB patients without infertility.
Results: The results showed that clinical features such as intermenstrual bleeding, endometrial synechiae, hydrosalpinx and endometritis appearance were the difference between two groups (p <0.001), those clinical features had a moderate correlation with the incidence of pulmonary tuberculosis women.
Conclusion: Clinical features like endometrial synechia and ultrasound imaging such as hydrosalpinx and endometritis encountered in pulmonary and extra pulmonary tuberculosis patients with infertility can be used as a basis for the diagnosis of alleged genital TB.

Keywords: infertility, genital tuberculosis, ultrasonography

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