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Clinical Profile of Covid-19 in Children, Review of Existing Literatures
Authors Tiruneh Tiyare F
Received 4 June 2020
Accepted for publication 25 August 2020
Published 21 September 2020 Volume 2020:11 Pages 385—392
DOI https://doi.org/10.2147/PHMT.S266063
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Professor Roosy Aulakh
Firew Tiyare Tiruneh
Department of Midwifery, College of Health Science, Mizan Tepi University, Mizan Teferi, Ethiopia
Correspondence: Firew Tiyare Tiruneh
Department of Midwifery, College of Health Science, Mizan Tepi University, PO Box- 260, Mizan Teferi, Ethiopia
Tel +251-917-83-0101
Email [email protected]
Abstract: WHO has confirmed that COVID-19 disease is a pandemic on March 11, 2020. The disease is caused by a new virus called SARS-CoV-2. Since, the pandemic was announced around 18,854,287 cases and 708,639 deaths were reported as of August 7, 2020. This review aimed to explore the etiology, pathogenesis, manifestation and complication. The phylogenetic study showed that SARS-CoV-2 is a single-stranded RNA virus. The virus is very contagious and has rapidly spread globally. Its unique structure called S glycoproteins help the virus enters in and cause infection in the body. Children’s body reacts against SARS-CoV-2 infections through the involvement of innate and adaptive immune system. The clinical manifestation in children is not specific and not determined. However, fever and cough have mostly been profiled. Though the severe condition is rarely reported in children compared with adults, life-threatening complications, and death associated with COVID-19 disease have been documented. Underlying chronic pulmonary disease, cardiovascular disease, immunosuppression, and obesity significantly contribute to the complications.
Keywords: SARS-CoV-2, COVID-19, children, pandemic, clinical profile
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