Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 6

Chronic airflow limitation in a rural Indian population: etiology and relationship to body mass index

Authors Chakrabarti B, Purkait S, Gun P, Moore VC, Choudhuri S, Zaman MJ, Warburton CJ, Calverley PMA, Mukherjee R

Published 18 October 2011 Volume 2011:6 Pages 543—549

DOI https://doi.org/10.2147/COPD.S24113

Review by Single-blind

Peer reviewer comments 2

Biswajit Chakrabarti1, Sabita Purkait2, Punyabrata Gun2, Vicky C Moore3, Samadrita Choudhuri4, MJ Zaman5,6, Christopher J Warburton1, Peter MA Calverley7, Rahul Mukherjee3
1Aintree Chest Centre, University Hospital Aintree, Liverpool, UK; 2Moitri Swasthya Kendra, Shramajibi Swasthya Udyog, Chengail, West Bengal, India; 3Department of Respiratory Medicine and Physiology, Birmingham Heartlands Hospital, Birmingham, UK; 4National Medical College, Birgunj, Nepal; 5Department of Epidemiology and Public Health, University College, London, UK; 6The George Institute for Global Health, Sydney, Australia; 7Clinical Sciences Centre, University Hospital Aintree, Liverpool, UK

Purpose: Respiratory conditions remain a source of morbidity globally. As such, this study aimed to explore factors associated with the development of airflow obstruction (AFO) in a rural Indian setting and, using spirometry, study whether underweight is linked to AFO.
Methods: Patients > 35 years old attending a rural clinic in West Bengal, India, took a structured questionnaire, had their body mass index (BMI) measured, and had spirometry performed by an ancillary health care worker.
Results: In total, 416 patients completed the study; spirometry was acceptable for analysis of forced expiratory volume in 1 second in 286 cases (69%); 16% were noted to exhibit AFO. Factors associated with AFO were: increasing age (95% confidence interval (CI) 0.004–0.011; P = 0.005), smoking history (95% CI 0.07–0.174; P = 0.006), male gender (95% CI 0.19–0.47; P = 0.012), reduced BMI (95% CI 0.19–0.65; P = 0.02), and occupation (95% CI 0.12–0.84; P = 0.08). The mean BMI in males who currently smoked (n = 60; 19.29 kg/m2; standard deviation [SD] 3.46) was significantly lower than in male never smokers (n = 33; 21.15 kg/m2 SD 3.38; P < 0.001). AFO was observed in 27% of subjects with a BMI <18.5 kg/m2, falling to 13% with a BMI ≥18.5 kg/m2 (P = 0.013). AFO was observed in 11% of housewives, 22% of farm laborers, and 31% of cotton/jute workers (P = 0.035).
Conclusion: In a rural Indian setting, AFO was related to advancing age, current or previous smoking, male gender, reduced BMI, and occupation. The data also suggest that being underweight is linked with AFO and that a mechanistic relationship exists between low body weight, smoking tobacco, and development of AFO.

Keywords: airflow obstruction, risk factors, BMI, spirometry, measurement, questionnaire, smoking, body weight

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Readers of this article also read:

Potential toxicity of dental nanomaterials to the central nervous system

Solla DF, Paiva TS, André M, Paiva WS

International Journal of Nanomedicine 2015, 10:5593-5596

Published Date: 3 September 2015

Sensitivity to environmental irritants and quality of life in COPD

Ternesten-Hasséus E, Larsson S, Millqvist E

International Journal of Chronic Obstructive Pulmonary Disease 2011, 6:685-691

Published Date: 9 December 2011

Severity of COPD at initial spirometry-confirmed diagnosis: data from medical charts and administrative claims

Mapel DW, Dalal AA, Blanchette CM, Petersen H, Ferguson GT

International Journal of Chronic Obstructive Pulmonary Disease 2011, 6:573-581

Published Date: 9 November 2011

Suppression of IL-8 production from airway cells by tiotropium bromide in vitro

Suzaki I, Asano K, Shikama Y, Hamasaki T, Kanei A, Suzaki H

International Journal of Chronic Obstructive Pulmonary Disease 2011, 6:439-448

Published Date: 6 September 2011

Disability related to COPD tool (DIRECT): towards an assessment of COPD-related disability in routine practice

Aguilaniu B, Gonzalez-Bermejo J, Regnault A, Dias Barbosa C, Arnould B, Mueser M, Granet G, Bonnefoy M, Similowski T

International Journal of Chronic Obstructive Pulmonary Disease 2011, 6:387-398

Published Date: 5 July 2011

Spirometric testing on World COPD Day

Tanja Grzetic-Romcevic, Boris Devcic, Silvana Sonc,

International Journal of Chronic Obstructive Pulmonary Disease 2011, 6:141-146

Published Date: 10 February 2011