Effects of Tissue-Bone Homeostasis Manipulation at Different Time Points on Pain and Brain Mechanisms in Patients with Knee Osteoarthritis Based on Circadian Rhythm: Study Protocol for a Randomized Controlled Trial

Ma H, Ding Y, Yang K, Zhang Z, Xu H, Feng W, Jiang L

Journal of Pain Research 2025, 18:4161-4172

Published Date: 19 August 2025