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Papers published by Dr Jan De Backer:


Exploring PI3Kδ Molecular Pathways in Stable COPD and Following an Acute Exacerbation, Two Randomized Controlled Trials

Begg M, Hamblin JN, Jarvis E, Bradley G, Mark S, Michalovich D, Lennon M, Wajdner HE, Amour A, Wilson R, Saunders K, Tanaka R, Arai S, Tang T, Van Holsbeke C, De Backer J, Vos W, Titlestad IL, FitzGerald JM, Killian K, Bourbeau J, Poirier C, Maltais F, Cahn A, Hessel EM

International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:1621-1636

Published Date: 3 June 2021

An Inhaled PI3Kδ Inhibitor Improves Recovery in Acutely Exacerbating COPD Patients: A Randomized Trial

Cahn A, Hamblin JN, Robertson J, Begg M, Jarvis E, Wilson R, Dear G, Leemereise C, Cui Y, Mizuma M, Montembault M, Van Holsbeke C, Vos W, De Backer W, De Backer J, Hessel EM

International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:1607-1619

Published Date: 3 June 2021

Airway Deposition of Extrafine Inhaled Triple Therapy in Patients with COPD: A Model Approach Based on Functional Respiratory Imaging Computer Simulations

Usmani OS, Scichilone N, Mignot B, Belmans D, Van Holsbeke C, De Backer J, De Maria R, Cuoghi E, Topole E, Georges G

International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:2433-2440

Published Date: 7 October 2020

Functional respiratory imaging: heterogeneity of acute exacerbations of COPD

van Geffen WH, Hajian B, Vos W, De Backer J, Cahn A, Usmani OS, Van Holsbeke C, Pistolesi M, Kerstjens HAM, De Backer W

International Journal of Chronic Obstructive Pulmonary Disease 2018, 13:1783-1792

Published Date: 30 May 2018

Changes in ventilation–perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling

Hajian B, De Backer J, Vos W, van Geffen WH, De Winter P, Usmani O, Cahn A, Kerstjens HAM, Pistolesi M, De Backer W

International Journal of Chronic Obstructive Pulmonary Disease 2018, 13:833-842

Published Date: 6 March 2018

Pathophysiological mechanism of long-term noninvasive ventilation in stable hypercapnic patients with COPD using functional respiratory imaging

Hajian B, De Backer J, Sneyers C, Ferreira F, Barboza KC, Leemans G, Vos W, De Backer W

International Journal of Chronic Obstructive Pulmonary Disease 2017, 12:2197-2205

Published Date: 28 July 2017

Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension

Hajian B, De Backer J, Vos W, Van Holsbeke C, Ferreira F, Quinn DA, Hufkens A, Claes R, De Backer W

International Journal of Chronic Obstructive Pulmonary Disease 2016, 11:1533-1541

Published Date: 5 July 2016

Functional respiratory imaging to assess the interaction between systemic roflumilast and inhaled ICS/LABA/LAMA

Vos W, Hajian B, De Backer J, Van Holsbeke C, Vinchurkar S, Claes R, Hufkens A, Parizel PM, Bedert L, De Backer W

International Journal of Chronic Obstructive Pulmonary Disease 2016, 11:263-271

Published Date: 4 February 2016

Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients

De Backer J, Vos W, Van Holsbeke C, Vinchurkar S, Claes R, Parizel PM, De Backer W

International Journal of Chronic Obstructive Pulmonary Disease 2013, 8:569-579

Published Date: 22 November 2013