Back to Browse Journals » Neuropsychiatric Disease and Treatment » Volume 3 » Issue 6

Sleep disturbances and suicide risk: A review of the literature

Authors Rebecca A Bernert, Thomas E Joiner

Published Date January 2007 Volume 2007:3(6) Pages 735—743

DOI http://dx.doi.org/10.2147/NDT.S1248

Published 20 January 2007

Rebecca A Bernert, Thomas E Joiner

Department of Psychology, Florida State University, Tallahassee, FL, USA

Abstract: A growing body of research indicates that sleep disturbances are associated with suicidal ideation and behaviors. This article (1) provides a critical review of the extant literature on sleep and suicidality and (2) addresses shared underlying neurobiological factors, biological and social zeitgebers, treatment implications, and future directions for research. Findings indicate that suicidal ideation and behaviors are closely associated with sleep complaints, and in some cases, this association exists above and beyond depression. Several cross-sectional investigations indicate a unique association between nightmares and suicidal ideation, whereas the relationship between insomnia and suicidality requires further study. Underlying neurobiological factors may, in part, account for the relationship between sleep and suicide. Serotonergic neurotransmission appears to play a critical role in both sleep and suicide. Finally, it remains unclear whether or not sleep-oriented interventions may reduce risk for suicidal behaviors. Unlike other suicide risk factors, sleep complaints may be particularly amenable to treatment. As a warning sign, disturbances in sleep may thus be especially useful to research and may serve as an important clinical target for future suicide intervention efforts.

Keywords: suicidality, sleep, nightmares, suicide risk factors

Download Article [PDF] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php

Readers of this article also read:

Effect of surface roughness on osteogenesis in vitro and osseointegration in vivo of carbon fiber-reinforced polyetheretherketone–nanohydroxyapatite composite

Deng Y, Liu X, Xu A, Wang L, Luo Z, Zheng Y, Deng F, Wei J, Tang Z, Wei S

International Journal of Nanomedicine 2015, 10:1425-1447

Published Date: 17 February 2015

Expression and prognostic relevance of MET and phospho-BAD in non-small cell lung cancer

Sun W, Ai T, Gao Y, Zhang Y, Cui J, Song L

OncoTargets and Therapy 2013, 6:1315-1323

Published Date: 18 September 2013

Anti-αvβ3 antibody guided three-step pretargeting approach using magnetoliposomes for molecular magnetic resonance imaging of breast cancer angiogenesis

Yan C, Wu Y, Feng J, Chen W, Liu X, Hao P, Yang R, Zhang J, Lin B, Xu Y, Liu R

International Journal of Nanomedicine 2013, 8:245-255

Published Date: 11 January 2013

Functionalized graphene oxide for clinical glucose biosensing in urine and serum samples

Veerapandian M, Seo YT, Shin H, Yun K, Lee MH

International Journal of Nanomedicine 2012, 7:6123-6136

Published Date: 18 December 2012

Management of attention-deficit hyperactivity disorder in adults: focus on methylphenidate hydrochloride

Rajasree Nair, Shannon B Moss

Neuropsychiatric Disease and Treatment 2009, 5:421-432

Published Date: 10 August 2009

Beneficial effect of pramipexole for motor function and depression in Parkinson’s disease

Osamu Kano, Ken Ikeda, Tetsuhito Kiyozuka, Konosuke Iwamoto, Hirono Ito, et al

Neuropsychiatric Disease and Treatment 2008, 4:707-710

Published Date: 16 February 2009

Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder

A Carlo Altamura, Jose M Goikolea

Neuropsychiatric Disease and Treatment 2008, 4:311-317

Published Date: 4 March 2008

The role of lamotrigine in the management of bipolar disorder

Felicity Ng, Karen Hallam, Nellie Lucas, Michael Berk

Neuropsychiatric Disease and Treatment 2007, 3:463-474

Published Date: 8 October 2007