Back to Browse Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 2 » Issue 4

Non-invasive ventilation in exacerbations of COPD

Authors Nicolino Ambrosino, Guido Vagheggini

Published 15 January 2008 Volume 2007:2(4) Pages 471—476

Nicolino Ambrosino, Guido Vagheggini

Pulmonary Unit. Cardio-Thoracic Department, University Hospital Pisa, Italy; Internal Medicine Unit. S. M. Maddalena General Hospital, Volterra, Italy

Abstract: Randomized controlled trials have confirmed the evidence and helped to define when and where non invasive mechanical ventilation (NIV) should be the first line treatment of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Noninvasive ventilation has its best indication in moderate-to-severe respiratory acidosis in patients with AECOPD. For this indication, studies conducted in ICU, in wards and in accident and emergency departments confirmed its effectiveness in preventing endotracheal intubation and reducing mortality. The skill of the health care team promotes proper NIV utilization and improves the patient outcome. Patients with severe acidosis or with altered levels of consciousness due to hypercapnic acute respiratory failure are exposed to high risk of NIV failure. In these patients a NIV trial may be attempted in closely monitored clinical settings where prompt endotracheal intubation may be assured.
Keywords: non-invasive positive pressure ventilation, COPD, acute respiratory failure

Download Article [PDF] 

Readers of this article also read:

Is asymptomatic peripheral arterial disease associated with walking endurance in patients with COPD?

Sun KS, Lin MS, Chen YJ, Chen YY, Chen SC, Chen W

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:1487-1492

Published Date: 29 July 2015

Development of acquired factor V inhibitor after treatment with ceftazidime: a case report and review of the literature

Cui QY, Shen HS, Wu TQ, Chen HF, Yu ZQ, Wang ZY

Drug Design, Development and Therapy 2015, 9:2395-2398

Published Date: 24 April 2015

Whole-body vibration improves functional capacity and quality of life in patients with severe chronic obstructive pulmonary disease (COPD): a pilot study

Braz Júnior DS, Dornelas de Andrade A, Teixeira AS, Cavalcanti CA, Morais AB, Marinho PE

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:125-132

Published Date: 12 January 2015

Pathophysiology of viral-induced exacerbations of COPD

Potena Alfredo, Caramori Gaetano, Casolari Paolo, Contoli Marco, Sebastian L Johnston, et al

International Journal of Chronic Obstructive Pulmonary Disease 2007, 2:477-483

Published Date: 15 January 2008

Factors affecting health status in COPD patients with co-morbid anxiety or depression

Minna J Hynninen, Ståle Pallesen, Inger Hilde Nordhus

International Journal of Chronic Obstructive Pulmonary Disease 2007, 2:323-328

Published Date: 15 October 2007