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Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases

Authors Zhang W, Chen J, Wu X, Chen L, Wei J, Xue M, Liang Q

Received 12 September 2019

Accepted for publication 10 February 2020

Published 17 February 2020 Volume 2020:13 Pages 405—412

DOI https://doi.org/10.2147/DMSO.S230799

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Antonio Brunetti


Weidong Zhang,* Jingfang Chen,* Xiaoming Wu, Luyu Chen, Jinxing Wei, Mingqiang Xue, Qingzheng Liang

Department of Thoracic Surgery, Henan Provincial Chest Hospital, Zhengzhou, Henan Province 450003, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Weidong Zhang Room 1, Weiwu Road, Zhengzhou City, Henan Province 450003, People’s Republic of China
Email zhangweidong0371@126.com

Objective: To analyse the clinical features of pneumomediastinum associated with DKA (diabetic ketoacidosis) to improve clinicians’ understanding of the disease.
Methods: A total of 78 patients with pneumomediastinum associated with DKA were identified in the literature search, and one patient treated in our hospital was included. The clinical features of the 79 patients were retrospectively analysed, and the pathogenesis, clinical symptoms, diagnostic methods, treatment strategies and prognoses were explored.
Results: All cases were confirmed by chest CT (computed tomography), and Kussmaul respiration, severe vomiting, chest pain were common symptoms. The main treatment principle was to correct acidosis and treat the primary disease. The majority of patients recovered within 1– 2 weeks, and only 2 patients died.
Conclusion: Pneumomediastinum associated with DKA is a rare disease, and it has a benign course when an early diagnosis is made and aetiological treatment is administered.

Keywords: pneumomediastinum, diabetic ketoacidosis, treatment, diagnosis

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