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Adherence to Guidelines for Assessment and Empiric Antibiotics Recommendations for Community-Acquired Pneumonia at Ambo University Referral Hospital: Prospective Observational Study

Authors Eticha EM, Gemechu WD

Received 21 December 2020

Accepted for publication 16 February 2021

Published 25 February 2021 Volume 2021:15 Pages 467—473


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen

Endalkachew Mekonnen Eticha,1 Workineh Diriba Gemechu2

1Ambo University, College of Medicine and Health Science, School of Pharmacy, Ambo, Ethiopia; 2Jigjiga University, College of Medicine and Health Science, School of Medicine, Jigjiga, Ethiopia

Correspondence: Endalkachew Mekonnen Eticha Email [email protected]

Objective: The high incidence and substantial morbidity and mortality associated with community-acquired pneumonia necessitate an accurate assessment and appropriate management of patients. This observational prospective study aimed to evaluate the physicians’ adherence to the Ethiopian Standard Treatment Guideline for assessment and an empiric antibiotic selection for Community-acquired pneumonia.
Results: The study indicated that the pneumonia severity assessment tool, CURB-65 score, was never used. Of 141 patients referred to an admitting diagnosis of severe community-acquired pneumonia, only 50 were subsequently found to satisfy the guideline criteria, over-diagnosis of 41.9%. Large proportions of the participants (130, 60%) were prescribed antibiotics in the last three months. The most commonly prescribed single antibiotic was Ceftriaxone (47, 21.7%), while ceftriaxone plus azithromycin was the most common combination, 110 (50.7%). In general, the extent of non-adherence to the national guideline for the use of antibiotics was 36.4%. In conclusion, the use of CRB65 scores was uncommon in the study setting. Poor adherence to Ethiopian Standard Treatment Guideline regarding the decision of hospital admission (41.9%) and the antimicrobial selection (36.4%) was determined.

Keywords: standard treatment, adherence, empiric antibiotics, community-acquired pneumonia

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