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Acute-onset postoperative endophthalmitis caused by multidrug-resistant Klebsiella pneumoniae

Authors Sanghi S, Pathengay A, Jindal A, Raval V, Nayak S, Sharma S, Bawdekar A, Flynn Jr H

Received 17 May 2014

Accepted for publication 18 June 2014

Published 16 September 2014 Volume 2014:8 Pages 1783—1785

DOI https://doi.org/10.2147/OPTH.S67894

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2


Shekhar Sanghi,1 Avinash Pathengay,1 Animesh Jindal,1 Vishal Raval,2 Sameera Nayak,2 Savitri Sharma,3 Abhishek Bawdekar,1 Harry W Flynn Jr4

1Department of Ophthalmology, L V Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, Andhra Pradesh, India; 2Department of Ophthalmology, L V Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India; 3Department of Microbiology, Jhaveri Microbiology Centre, L V Prasad Eye Institute, KAR Campus, Hyderabad, Andhra Pradesh, India; 4Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USA

Abstract: The purpose of this paper is to report outcomes of intravitreal imipenem in the treatment of multidrug-resistant Klebsiella-related postoperative endophthalmitis. This observational case series consists of three eyes from three patients seen between 2013 and 2014. Multidrug-resistant Klebsiella pneumoniae is characterized by a rapid, fulminant course and severe intraocular inflammation. Intravitreal imipenem may be used to treat such infection.

Keywords: postoperative endophthalmitis, Klebsiella pneumoniae, imipenem, multidrug resistance

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