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A simple and rapid test of physical performance in chronic obstructive pulmonary disease

Authors Albarrati, Gale N, Enright S, Munnery M, Cockcroft J, Shale D

Received 10 February 2016

Accepted for publication 27 April 2016

Published 2 August 2016 Volume 2016:11(1) Pages 1785—1791

DOI https://doi.org/10.2147/COPD.S106151

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Professor Hsiao-Chi Chuang

Peer reviewer comments 3

Editor who approved publication: Dr Richard Russell


Ali Mufraih Albarrati,1 Nichola S Gale,1 Stephanie Enright,1 Margaret M Munnery,2 John R Cockcroft,2 Dennis J Shale2

1Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK; 2Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK

Abstract: Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal study of comorbidities in COPD, submaximal physical performance was determined in 520 patients and 150 controls using the TUG test and 6MWD. Spirometry, body composition, handgrip strength, the COPD assessment test, St George’s Respiratory Questionnaire (SGRQ), and the modified Medical Research Council dyspnoea scale were also determined. Patients and controls were similar in age, body mass index, and sex proportions. The TUG in the patients was greater than that in the control group, P=0.001, and was inversely related to 6MWD (r=–0.71, P<0.001) and forced expiratory volume in one second predicted (r=–0.19, P<0.01) and was directly related to the SGRQ activity (r=0.39, P<0.001), SGRQ total (r=0.37, P<0.001), and total COPD assessment test scores (r=0.37, P<0.001). The TUG identified the difference in physical performance between patients and controls. The TUG test and validated questionnaires provide a measure of physical performance, which is rapid and could be used in clinical practice.

Keywords: COPD, physical inactivity, timed up and go test

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