Back to Journals » OncoTargets and Therapy » Volume 13

A Serosa-Originated Gastric Stromal Tumor Misdiagnosed by Ultrasonography and Frozen Section Pathology: A Case Report

Authors Ren L, Qian H, Wang J, Jin P, Hu Q, Yu J, Zhang X, Zhang Y, Huang H

Received 5 April 2020

Accepted for publication 30 May 2020

Published 19 June 2020 Volume 2020:13 Pages 5831—5835

DOI https://doi.org/10.2147/OTT.S257013

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Prof. Dr. Nicola Silvestris


Lizhong Ren,1,* Hongrong Qian,1,* Junsen Wang,2 Piaopiao Jin,3 Qida Hu,4 Jiajie Yu,5 Xin Zhang,6 Yun Zhang,4 Haifeng Huang5

1Department of Ultrasound, Shengzhou People’s Hospital, Shaoxing 312400, People’s Republic of China; 2Department of Pathology, Shengzhou People’s Hospital, Shaoxing 312400, People’s Republic of China; 3Health Management Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of China; 4Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of China; 5Department of Surgery, Shengzhou People’s Hospital, Shaoxing 312400, People’s Republic of China; 6Department of Radiology, Shengzhou People’s Hospital, Shaoxing 312400, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Junsen Wang
Department of Pathology, Shengzhou People’s Hospital, 666 Dangui Road, Shaoxing 312400, People’s Republic of China
Tel +86 575 8333 8221
Email junsenwang@outlook.com
Haifeng Huang
Department of Surgery, Shengzhou People’s Hospital, 666 Dangui Road, Shaoxing 312400, People’s Republic of China
Tel +86 575 8333 8570
Email 18241425@qq.com

Abstract: Gastric gastrointestinal stromal tumor (GIST) is a mesenchymal neoplasm, typically arising from the muscularis propria layer of the stomach wall. Serosa-derived GIST is rarely seen and has not been reported yet. A 49-year-old Chinese female was presented with marked abdominal distension. Ultrasonography revealed a retroperitoneal tumor adjacent to the stomach wall with an intact structure of five echo layers, indicating a non-stomach tumor origin. Preoperative radiological studies suggested tight tumor-stomach adjacency, which was confirmed by intraoperative dissection. Initial frozen section indicated a pathological diagnosis of spindle cell tumor, which turned out to be a gastric GIST originated from the serosa layer of the stomach wall. The current case demonstrates the rare occurrence of serosa-derived GIST. This case also suggests difficulties in preoperative diagnosis of gastric GISTs, especially when uncommon pathological conditions like rare tumor origins were presented.

Keywords: gastric gastrointestinal stromal tumor, serosa layer, schwannoma, misdiagnosis

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]