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Xanthelasma palpebrarum – a brief review

Authors Nair PA, Singhal R

Received 30 June 2017

Accepted for publication 13 October 2017

Published 18 December 2017 Volume 2018:11 Pages 1—5

DOI https://doi.org/10.2147/CCID.S130116

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Jeffrey Weinberg

Video abstract presented by Pragya A Nair.

Views: 47

Pragya A Nair, Rochit Singhal

Department of Dermatology, Venereology and Leprosy, Pramukhswami Medical College, Gujarat, India

Abstract: Xanthelasma palpebrarum is the most common cutaneous xanthoma, characterized by yellowish plaques over eyelids – most commonly, over the inner canthus of the upper lid. It is triggered by hyperlipidemia, thyroid dysfunction, and diabetes mellitus. Xanthelasma results from perivascular infiltration of mono- and multinucleated foam cells within lipid-laden cytoplasmic vacuoles in the superficial reticular dermis. Different modalities of treatment, such as simple surgical excision, cryotherapy, chemical peeling with trichloroacetic acid, radiofrequency, and laser, are used in the treatment of xanthelasma palpebrarum. A brief review of current treatment strategies is presented here.

Keywords: xanthelasma palpebrarum, xanthoma, hyperlipidemia, laser, cryotherapy

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