Back to Journals » Open Access Journal of Clinical Trials » Volume 4

Variation in effect of intervention studies in research on sickness absence

Authors Soegaard HJ

Received 30 August 2011

Accepted for publication 12 March 2012

Published 24 April 2012 Volume 2012:4 Pages 1—20


Review by Single anonymous peer review

Peer reviewer comments 3

Hans Joergen Soegaard
Research Unit West, Centre for Psychiatric Research, Aarhus University Hospital, Risskov

Background: Intervention studies in sickness absence research demonstrate a low effect and ambiguous results in reducing sickness absence and improving work status. The aim of this study was to determine if the effect of interventions is related to type of intervention, target population, inclusion criteria used, and impact of the scientific quality of the studies.
Methods: Based on a structured review of 57 studies, short-term, medium-term, and long-term effects were analyzed with regard to the type of intervention, target population, inclusion criteria, and scientific quality of the studies.
Results: The overall result was that the effect rate was low, ie, about 20% for short-term effect (up to 6 months) and medium-term effect (6–12 months), and 40% for long-term effect (≥12 months). Interventions using stress reduction were most effective with regard to short-term and medium-term effects, whereas collaborative care was most effective for long-term effects. The effects were related to the inclusion criteria and, to a minor degree, to the scientific quality of the studies.
Conclusion: In the field of sickness absence research, more attention should be paid to the interrelationship between the types of interventions, target populations, and inclusion criteria for the studies. Larger studies of high methodological quality are needed. Steps should be taken to standardize outcome measures.

Keywords: nonparticipation, sickness absence, return to work, controlled trial, review

Creative Commons License © 2012 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.