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Validation of sensor for postoperative positioning with intraocular gas

Authors Brodie F, Woo K, Balakrishna A, Choo H, Grubbs R

Received 29 January 2016

Accepted for publication 31 March 2016

Published 25 May 2016 Volume 2016:10 Pages 955—960

DOI https://doi.org/10.2147/OPTH.S105347

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Gokcen Gökçe

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Frank L Brodie,1 Kelly Y Woo,2 Ashwin Balakrishna,2 Hyuck Choo,2 Robert H Grubbs2

1Department of Ophthalmology, University of California San Francisco, San Francisco, 2Department of Medical Engineering, California Institute of Technology, Pasadena, CA, USA

Purpose: Surgical repair of retinal attachment or macular hole frequently requires intraocular gas. This necessitates specific postoperative positioning to improve outcomes and avoid complications. However, patients struggle with correct positioning. We have developed a novel sensor to detect the position of the gas bubble in the eye and provide feedback to patients in real time. In this paper, we determine the specificity and sensitivity of our sensor in vitro using a model eye.
Methods: We assessed the reliability of our sensor to detect when a gas bubble has deviated off a model retinal break in a model eye. Various bubble sizes representing the intraocular kinetics of sulfur hexafluoride gas and varying degrees of deviation from the correct position were tested using the sensor attached to a mannequin head with a model eye.
Results:
We recorded 36 data points. The sensor acted appropriately in 33 (91.7%) of them. The sensor triggered the alarm every time the bubble deviated off the break (n=15, sensitivity =100%). However, it triggered the alarm (falsely) 3/21 times when the bubble was correctly positioned over the retinal break (specificity =86%).
Conclusion:
Our device shows excellent sensitivity (100%) and specificity (86%) in detecting whether intraocular gas is tamponading a retinal break in a model eye.

Keywords:
postoperative positioning, intraocular gas, vitrectomy, retinal detachment, macular hole, pneumatic retinopexy

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