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Uncontrolled hypertension and orthostatic hypotension in relation to standing balance in elderly hypertensive patients

Authors Shen SS, He T, Chu JJ, He J, Chen XJ

Received 21 January 2015

Accepted for publication 26 March 2015

Published 28 May 2015 Volume 2015:10 Pages 897—906

DOI https://doi.org/10.2147/CIA.S81283

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Professor Zhi-Ying Wu

Shanshan Shen,1 Ting He,1 Jiaojiao Chu,1 Jin He,2 Xujiao Chen1

1Department of Geriatrics, Zhejiang Hospital, Hangzhou, 2Department of Neurology, Fuyuan Hospital of Yiwu, Jinhua, People’s Republic of China

Objective: To investigate the associations among uncontrolled hypertension, orthostatic hypotension (OH), and standing balance impairment in the elderly hypertensive patients referred to comprehensive geriatric assessment (CGA).
Methods: In a cross-sectional study, a total of 176 elderly hypertensive patients who underwent CGA were divided into OH group (n=36) and non-OH group (n=140) according to blood pressure measurement in the supine position, after immediate standing up, and after 1 minute and 3 minutes of standing position. Uncontrolled hypertension was defined as blood pressure of ≥140/90 mmHg if accompanied by diabetes mellitus (DM) or chronic kidney disease (CKD), or ≥150/90 mmHg if no DM and no CKD. Standing balance, including immediate standing balance and prolonged standing balance, was assessed in side-by-side and tandem stance.
Results: Neither uncontrolled hypertension nor OH was associated with prolonged standing balance impairment in elderly hypertensive patients (P>0.05). Blood pressure decrease after postural change was significantly associated with immediate standing balance impairment in side-by-side and tandem stance (P<0.05). Patients with OH were at greater risk of immediate standing balance impairment in both side-by-side and tandem stance than those without OH (odds ratio [OR] 3.44, 95% confidence interval [CI] 1.26–9.33, P<0.05; OR 3.14, 95% CI 1.14–8.64, P<0.01). Furthermore, uncontrolled hypertension was associated with immediate standing balance impairment in side-by-side stance (OR 2.96, 95% CI 1.31–6.68, P<0.05).
Conclusion: Uncontrolled hypertension, OH, and blood pressure decrease after postural change were associated with immediate standing balance impairment, and therefore, a better understanding of the underlying associations might have major clinical value.

Keywords: hypertension, orthostatic hypotension, balance, elderly

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