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Toxicant-associated steatohepatitis: à propos a case of benzene exposure

Authors Benharroch D, Talalay B

Received 23 August 2016

Accepted for publication 2 November 2016

Published 6 March 2017 Volume 2017:10 Pages 73—75

DOI https://doi.org/10.2147/IMCRJ.S120422

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Professor Allan Spigelman


Daniel Benharroch,1 Boris Talalay2

1Department of Pathology, 2Department of Family Medicine, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

Abstract: An attempted interpretation of recurrent episodes of hepatitis in a girl at ages 6 and 13 years, which were followed by an interval of 35 years of apparent good health, is reported. A subsequent transient incidence of a halothane hypersensitivity reaction at age 48 years led to the disclosure of negative hepatitis A, B and C antigenicity. A tentative diagnosis may be reached if we accept, at its face value, the statement that a toy that the child played with before each hepatitis episode carried a very high benzene content. The toy was a “pate-à-ballon” or “magic balloon,” and it can carry a benzene content that is seven to nine times higher than the traditionally authorized concentration.

Keywords: toxic hepatitis, volatile organic compound

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