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The use of transcatheter aortic valve replacement vs surgical aortic valve replacement for the treatment of aortic stenosis

Authors Jensen H, Tsai L, Thourani V

Received 12 May 2015

Accepted for publication 2 July 2015

Published 25 August 2015 Volume 2015:6 Pages 105—116

DOI https://doi.org/10.2147/RRCC.S71379

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Di Lang

Peer reviewer comments 3

Editor who approved publication: Dr Richard Kones

Hanna A Jensen, Lillian L Tsai, Vinod H Thourani

Division of Cardiothoracic Surgery, Joseph B Whitehead Department of Surgery, Structural Heart and Valve Center, Emory University School of Medicine, Atlanta, GA, USA

Abstract: Severe aortic stenosis (AS) is associated with considerable morbidity and mortality and is increasing in prevalence as the global population increases. Since AS primarily affects the elderly, many of these patients have comorbidities that make them poor candidates for the gold standard treatment for AS, surgical aortic valve replacement. Transcatheter aortic valve replacement has emerged as a novel technology for the management of AS in higher risk patients over the past decade. Randomized trials have established the safety and efficacy of transcatheter aortic valve replacement, and the medical community has rallied to identify the patients who are most suitable for this transformative treatment. This review focuses on outlining the key procedural differences, describing the unique challenges of both operations, and finally assessing and comparing outcomes both on a general level and in challenging patient subgroups.

Keywords: aortic valve replacement, transcatheter aortic valve replacement, surgical aortic valve replacement
 

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