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The Impact of Treatment Adherence on Quality of Life Among Type 2 Diabetes Mellitus Patients – Findings from a Cross-Sectional Study

Authors Majeed A, Rehman M, Hussain I, Imran I, Saleem MU, Saeed H, Hashmi FK, Akbar M, Abrar MA, Ramzan B, Chaudhry MO, Islam M, Nisar N, Rasool MF

Received 3 December 2020

Accepted for publication 6 February 2021

Published 26 February 2021 Volume 2021:15 Pages 475—481

DOI https://doi.org/10.2147/PPA.S295012

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen


Abdul Majeed,1 Muhammad Rehman,1 Iltaf Hussain,1 Imran Imran,2 Muhammad Usman Saleem,3 Hamid Saeed,4 Furqan K Hashmi,4 Muqarrab Akbar,5 Muhammad Asad Abrar,1 Basit Ramzan,6 Muhammad Omer Chaudhry,7 Muhammad Islam,4 Naveed Nisar,8 Muhammad Fawad Rasool1

1Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan; 2Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan; 3Department of Biosciences, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan; 4University College of Pharmacy, University of the Punjab, Allama Iqbal Campus, Lahore, 54000, Pakistan; 5Department of Political Science, Bahauddin Zakariya University, Multan, 60800, Pakistan; 6Al Shifa Pharmacy, Multan, Pakistan; 7School of Economics, Bahauddin Zakariya University, Multan, 60800, Pakistan; 8Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan

Correspondence: Muhammad Fawad Rasool
Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University Multan, Multan, Pakistan
Tel +923008639046
Email [email protected]

Aim: The current study was conducted to assess the factors contributing to treatment adherence and its impact on the quality of life (QoL) in type 2 diabetes mellitus (T2DM) patients.
Methods: A cross-sectional study was conducted between January 2020 to March 2020 among T2DM patients. The data was collected from T2DM out-patient clinics. The participants were recruited by using a simple random sampling method. To assess the association of demographics with the level of adherence, binary logistics regression analysis was applied. Moreover, the Mann–Whitney U-test was used to evaluate the impact of adherence on QoL.
Results: A total of 384 patients participated in this study. Amongst them, 60.2% were male and 39.8% were female. Low adherence was seen in illiterate patients and patients older than 40 years. The results showed that good QoL in T2DM patients was significantly associated with treatment adherence (p= 0.004).
Conclusion: The finding of the current study showed that the non-adherence prevailed in illiterate strata of the study population and the medication adherence significantly affects the QoL in T2DM patients. These findings suggest that health regulatory agencies should focus on implementing disease-education interventions for improving the adherence to medications in patients with long-term conditions.

Keywords: type 2 diabetes, drug adherence, quality of life

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