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Temporomandibular disorders in patients with schizophrenia using antipsychotic agents: a discussion paper

Authors Nogueira de Araújo A, Alves do Nascimento M, de Sena E, Baptista A

Received 7 November 2013

Accepted for publication 3 January 2014

Published 10 March 2014 Volume 2014:6 Pages 21—27

DOI https://doi.org/10.2147/DHPS.S57172

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4


Arão Nogueira de Araújo,1 Marion Alves do Nascimento,1 Eduardo Pondé de Sena,1,2 Abrahão Fontes Baptista3,4

1Postgraduate Program in Interactive Processes of Organs and Systems, 2Department of Pharmacology, Institute of Health Sciences, 3Department of Biomorphology, Institute of Health Sciences, 4Postgraduate Program in Medicine and Health, Federal University of Bahia, Salvador, Brazil

Abstract: Patients with psychiatric problems show a tendency to develop temporomandibular disorders (TMD). Particularly, patients with schizophrenia are quite likely to have signs and symptoms of TMD due to the impairment of their oral health, the use of antipsychotic drugs, and other general health problems. In nonschizophrenic populations, TMD have been considered as the main cause of nondental pain in the orofacial region, involving mechanisms associated with changes in masticatory activity at the cortical and neuromuscular levels. Individuals with schizophrenia do not usually complain of pain, and TMD is misdiagnosed in this population. In this paper, we aimed to review the clinical aspects of TMD in people with schizophrenia on antipsychotic drug therapy.

Keywords: schizophrenia, temporomandibular joint, pain, antipsychotic agents

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