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Targeted temperature management in emergency medicine: current perspectives

Authors Hunter B, Ellender T

Received 19 June 2015

Accepted for publication 19 August 2015

Published 28 September 2015 Volume 2015:7 Pages 69—77

DOI https://doi.org/10.2147/OAEM.S71279

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Hans-Christoph Pape


Benton R Hunter,1 Timothy J Ellender1,2

1Department of Emergency Medicine, 2Department of Critical Care Medicine, Indiana University School of Medicine, Indiana University, Indianapolis, IN, USA

Abstract: Landmark trials in 2002 showed that therapeutic hypothermia (TH) after out-of-hospital cardiac arrest due to ventricular tachycardia or ventricular fibrillation resulted in improved likelihood of good neurologic recovery compared to standard care without TH. Since that time, TH has been frequently instituted in a wide range of cardiac arrest patients regardless of initial heart rhythm. Recent evidence has evaluated how, when, and to what degree TH should be instituted in cardiac arrest victims. We outline early evidence, as well as recent trials, regarding the use of TH or targeted temperature management in these patients. We also provide evidence-based suggestions for the institution of targeted temperature management/TH in a variety of emergency medicine settings.

Keywords: therapeutic hypothermia, cardiac arrest, heart arrest

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