Back to Journals » International Journal of Nanomedicine » Volume 10 » Issue 1

Synthesis and anti-fungal effect of silver nanoparticles–chitosan composite particles

Authors Wang LS, Wang CY, Yang CH, Hsieh CL, Chen SY, Shen CY, Wang JJ, Huang KS

Received 12 November 2014

Accepted for publication 5 January 2015

Published 1 April 2015 Volume 2015:10(1) Pages 2685—2696

DOI https://doi.org/10.2147/IJN.S77410

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Thomas J Webster

Lung-Shuo Wang,1–4 Chih-Yu Wang,2 Chih-Hui Yang,5 Chen-Ling Hsieh,3,5 Szu-Yu Chen,3,5 Chi-Yen Shen,1 Jia-Jung Wang,2 Keng-Shiang Huang3

1Department of Electrical Engineering, I-Shou University, Kaohsiung, Taiwan; 2Department of Biomedical Engineering, I-Shou University, Kaohsiung, Taiwan; 3The School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan; 4Department of Chinese Medicine, E-Da Hospital, Kaohsiung, Taiwan; 5Department of Biological Science and Technology, I-Shou University, Kaohsiung, Taiwan

Abstract: Silver nanoparticles have been used in various fields, and several synthesis processes have been developed. The stability and dispersion of the synthesized nanoparticles is vital. The present article describes a novel approach for one-step synthesis of silver nanoparticles–embedded chitosan particles. The proposed approach was applied to simultaneously obtain and stabilize silver nanoparticles in a chitosan polymer matrix in-situ. The diameter of the synthesized chitosan composite particles ranged from 1.7 mm to 2.5 mm, and the embedded silver nanoparticles were measured to be 15±3.3 nm. Further, the analyses of ultraviolet-visible spectroscopy, energy dispersive spectroscopy, and X-ray diffraction were employed to characterize the prepared composites. The results show that the silver nanoparticles were distributed over the surface and interior of the chitosan spheres. The fabricated spheres had macroporous property, and could be used for many applications such as fungicidal agents in the future.

Keywords: silver, nanoparticles, chitosan, anti-fungal

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Readers of this article also read:

Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera

Marslin G, Selvakesavan RK, Franklin G, Sarmento B, Dias ACP

International Journal of Nanomedicine 2015, 10:5955-5963

Published Date: 22 September 2015

Small molecules against B-RAF (BRAF) Val600Glu (V600E) single mutation

Zaharie F, Cojocneanu-Petric R, Muresan M, Frinc I, Dima D, Petrushev B, Tanase A, Berce C, Chitic M, Berindan-Neagoe I, Pileczki V, Irimie A, Tomuleasa C

International Journal of Nanomedicine 2015, 10:4897-4899

Published Date: 31 July 2015

A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting

Wang SM, He X, Li N, Yu F, Hu Y, Wang LS, Zhang P, Du YK, Du SS, Yin ZF, Wei YR, Mulet X, Coia G, Weng D, He JH, Wu M, Li HP

International Journal of Nanomedicine 2015, 10:2857-2869

Published Date: 13 April 2015

Accessing to the minor proteome of red blood cells through the influence of the nanoparticle surface properties on the corona composition

Zaccaria A, Roux-Dalvai F, Bouamrani A, Mombrun A, Mossuz P, Monsarrat B, Berger F

International Journal of Nanomedicine 2015, 10:1869-1883

Published Date: 9 March 2015

Mesenchymal stromal cell labeling by new uncoated superparamagnetic maghemite nanoparticles in comparison with commercial Resovist – an initial in vitro study

Skopalik J, Polakova K, Havrdova M, Justan I, Magro M, Milde D, Knopfova L, Smarda J, Polakova H, Gabrielova E, Vianello F, Michalek J, Zboril R

International Journal of Nanomedicine 2014, 9:5355-5372

Published Date: 20 November 2014

Enhanced antidepressant-like effects of the macromolecule trefoil factor 3 by loading into negatively charged liposomes

Qin J, Yang X, Mi J, Wang J, Hou J, Shen T, Li Y, Wang B, Li X, Zhu W

International Journal of Nanomedicine 2014, 9:5247-5257

Published Date: 12 November 2014

Multifunctional materials for bone cancer treatment

Marques C, Ferreira JMF, Andronescu E, Ficai D, Sonmez M, Ficai A

International Journal of Nanomedicine 2014, 9:2713-2725

Published Date: 28 May 2014

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010