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Successful treatment of reactive airways dysfunction syndrome by high-dose vitamin D

Authors Varney V, Evans, Bansal A

Published 22 September 2011 Volume 2011:4 Pages 87—91

DOI https://doi.org/10.2147/JAA.S19107

Review by Single anonymous peer review

Peer reviewer comments 2


Veronica A Varney1, Jane Evans1, Amolak S Bansal2
1Department of Respiratory Medicine, 2Department of Immunology and Allergy, St. Helier Hospital, Carshalton, Surrey, UK

Abstract: Reactive airways dysfunction syndrome is a controversial and poorly understood condition produced by inhalational injury from gas, vapors, or fumes. The symptoms mimic asthma, but appear unresponsive to asthma treatments. If symptoms persist for more than 6 months, there is a risk that they can become chronic. For these cases, effective treatments are lacking and quality of life is poor. We describe the first use of high-dose vitamin D in a patient with this condition, who fulfilled the 1995 American College of Chest Physicians criteria for this syndrome. The patient we describe presented an extremely difficult management problem and was refractory to conventional treatments, but responded to high-dose oral vitamin D supplements.

Keywords: asthma, vitamin D, reactive airways dysfunction syndrome, cough, inhalational injury

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