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Spectral domain optical coherence tomography documented rapid resolution of pseudophakic cystoid macular edema with topical difluprednate

Authors Chalam K, Khetpal V, Patel CJ

Received 11 November 2011

Accepted for publication 5 January 2012

Published 24 January 2012 Volume 2012:6 Pages 155—158

DOI https://doi.org/10.2147/OPTH.S28151

Review by Single-blind

Peer reviewer comments 3


KV Chalam, Vijay Khetpal, Chirag J Patel
Department of Ophthalmology, University of Florida Jacksonville, FL, USA

Introduction: Pseudophakic cystoid macular edema is a common cause of poor vision after cataract surgery, and topical corticosteroids and nonsteroidal anti-inflammatory drugs are used for its treatment. We investigated the effectiveness of difluprednate (Durezol®, recently approved by the US Food and Drug Administration) in the treatment of cystoid macular edema, assisted with spectral domain optical coherence tomography (SD-OCT).
Case report: A 63-year-old African-American woman presented 6 weeks after uneventful cataract surgery in her left eye with decreased vision and associated distortion of the central visual field. Fluorescein angiogram and SD-OCT confirmed pseudophakic cystoid macular edema. Difluprednate was topically administered twice daily and monitored with serial imaging. Resolution was noted after 1 month of topical therapy, with improvement in visual acuity and resolution of distortion.
Conclusion: Difluprednate is an effective treatment for patients with severe pseudophakic cystoid macular edema. SD-OCT allows the physician to monitor resolution of the macular edema easily.

Keywords: cystoid macular edema, difluprednate, spectral domain optical coherence tomography, pseudophakic

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