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Sodium valproate-induced enuresis in a pediatric bipolar patient
Authors Cheng W, Lin X, Lu D , Luo L
Received 22 August 2013
Accepted for publication 3 September 2013
Published 31 October 2013 Volume 2013:9 Pages 1671—1672
DOI https://doi.org/10.2147/NDT.S53388
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Wentao Cheng,1,* Xiaoling Lin,2,* Dali Lu1
1Department of Pediatric and Geriatric Psychiatry, Fuzhou Neuropsychiatric Hospital, Fuzhou, Fujian, People's Republic of China; 2School of Nursing of Central South University, Changsha, Hunan, People's Republic of China
*These authors contributed equally to this work
Abstract: Sodium valproate (SV) is effective and well tolerated for the treatment of epilepsy and mood disorders. There are several cases of SV-induced enuresis noted in epileptic patients. No alternative medication has been suggested to manage this problem. We present the first case of a pediatric bipolar patient who developed diurnal and nocturnal enuresis during SV therapy. Clinicians should be aware of this side effect, as it has not been reported in nonepileptic patients, and it may be detrimental to treatment adherence.
Keywords: sodium valproate, enuresis, bipolar disorder
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