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Smartphone applications for chronic pain management: a critical appraisal

Authors Alexander J, Joshi G

Received 17 August 2016

Accepted for publication 26 August 2016

Published 26 September 2016 Volume 2016:9 Pages 731—734


Checked for plagiarism Yes

Editor who approved publication: Dr Michael E Schatman

John C Alexander, Girish P Joshi

Department of Anesthesiology & Pain Management, University of Texas Southwestern Medical Center, Dallas, TX, USA

Chronic pain is a common condition with significant detrimental physical, psychological, social, and economic impact. The Institute of Medicine estimates that >100 million Americans suffer from chronic pain,1 representing approximately one-third of the entire population of the US.2 Conservative estimates suggest that well over US $500 billion per year is spent in the treatment of these pain conditions, not to mention the lost productivity of these individuals or the burden that their suffering engenders for patients and their families. Despite tremendous efforts, chronic pain continues to be a major societal problem.1
Smartphones have become one of the most rapidly adopted technologies in the modern history of mankind allowing for previously unimaginable opportunities for communication and access to information.3 Powering this societal revolution is not so much the onboard or attachable hardware for smartphones, but the dizzying array of software programs that use the hardware to add novel functions; we call the unifying software programs “applications” or, more commonly, “apps”. While each phone comes with onboard technologies, such as Wi-Fi, Bluetooth, lights, microphones, cameras, accelerometers, and even barometers, it is the development of the app that combines these functionalities to create new and innovative uses for the same hardware for everything from Skype4 to Pokémon GO.5
The use of such applications within the health care industry continues to grow, and it is estimated that the market for mobile health apps will grow to US$26 billion in 2017.6 The immense size of this market is due to the functional flexibility that apps can provide. These emerging technologies also provide new opportunities to engage with patients and improve health care outcomes. Studies have shown that mobile phone messaging helps to improve patient engagement outside the clinic or hospital and facilitates self-management of chronic diseases such as hypertension, diabetes, and asthma,7 and app-based systems may also be of use in this regard. While the overall market for apps in health care is robust, the market segment for pain management is less than impressive.


The authors report no conflicts of interest in this work.



Institute of Medicine of the National Academies. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research. Washington, DC: National Academies Press (US); 2011.


United States Census Bureau. Vintage 2011: National Tables. Available from: Accessed August 9, 2016.


Flurry Insights. iOs and Android Adoption Explodes Internally. 2016. Available from: Accessed April 27, 2016.


Skype Communications S.a.r.l. Skype-for-iPhone. Available from: Accessed August 9, 2016


Niantic, Inc. Pokémon GO. Available from: Accessed August 1, 2016


Research2guidance. Mobile Health Market Report 2013–2017. 2013. Available from: Accessed August 9, 2016.


McEvoy MD, Hand WR, Stiegler MP, et al. A Smartphone-based Decision Support Tool Improves Test Performance Concerning Application of the Guidelines for Managing Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy. Anesthesiology. 2016;124:186–198.


Schatman ME. Interdisciplinary chronic pain management: international perspectives. Pain. 2012;20(7):1e–5e.


de Jongh T, Gurol-Urganci I, Vodopivec-Jamsek V, Car J, Atun R. Mobile phone messaging for facilitating self-management of long-term illnesses. Cochrane Database Syst Rev. 2012;2(12):CD007459.


Vardeh D, Edwards RR, Jamison RN, Eccleston C. There’s an App for That: Mobile Technology Is a New Advantage in Managing Chronic Pain. Pain. 2013;XXI(6):1–7.


Fisher E, Law E, Palermo T, Eccleston C. Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev. 2015;3(3):CD011118.


CMS. National Health Expenditures 2014 Highlights. Available from: Accessed August 9, 2016.


Industry Research: Healthcare. 2016 Connected Patient Report: Insights into patient preferences on telemedicine, wearables and post-discharge care. Available from: Accessed August 9, 2016.


Lalloo C, Jibb LA, Rivera J, Agarwal A, Stinson JN. “There’s a Pain App for That”: Review of Patient-targeted Smartphone Applications for Pain Management. Clin J Pain. 2015;31:557–563.


Reynoldson C, Stones C, Allsop M, et al. Assessing the quality and usability of smartphone apps for pain self-management. Pain Med. 2014;15:893–909.


Rosser BA, Eccleston C. Smartphone applications for pain management. J Telemed Telecare. 2011;17:308–312.


Alexander JC, Joshi GP. Smartphone Application-based Medical Devices: Twenty-first Century Data Democratization or Anarchy? Anesth Analg. Epub 2016 Aug 22.


Mobile Medical Applications: Guidance for Industry and Food & Drug Administration Staff. Available from: Accessed August 9, 2016.


S Misra. New report finds more than 165,000 mobile health apps now available, takes close look at characteristics & use; 2015. Available from: Accessed August 9, 2016.


Alexander JC, Minhajuddin A, Joshi GP. Comparison of smartphone application-based vital sign monitors without external hardware versus those used in clinical practice: a prospective trial. J Clin Monit Comput. Epub 2016 May 12.


Plante TB, Urrea B, MacFarlane ZT, et al. Validation of the Instant Blood Pressure Smartphone App. JAMA Intern Med. 2016;176:700–702.


Blodt S, Pach D, Roll S, Witt CM. Effectiveness of app-based relaxation for patients with chronic low back pain (Relaxback) and chronic neck pain (Relaxneck): study protocol for two randomized pragmatic trials. Trials. 2014;15:490.


de la Vega R, Roset R, Castarlenas E, Sanchez-Rodriguez E, Sole E, Miro J. Development and testing of painometer: a smartphone app to assess pain intensity. J Pain. 2014;15:1001–1007.


Stinson JN, Lalloo C, Harris L, et al. iCanCope with Pain™: User-centered design of a web- and mobile-based self-management program for youth with chronic pain based on identified health care needs. Pain Res Manag. 2014;19:257–265.

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