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Short-term tocolytics for preterm delivery – current perspectives

Authors Haas D, Benjamin T, Sawyer R, Quinney S

Received 15 November 2013

Accepted for publication 17 December 2013

Published 27 March 2014 Volume 2014:6 Pages 343—349

DOI https://doi.org/10.2147/IJWH.S44048

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2


David M Haas, Tara Benjamin, Renata Sawyer, Sara K Quinney

Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, USA

Abstract: Administration of short-term tocolytic agents can prolong pregnancy for women in preterm labor. Prolonging pregnancy has many benefits because it allows for other proven interventions, such as antenatal corticosteroid administration, to be accomplished. This review provides an overview of currently utilized tocolytic agents and the evidence demonstrating their efficacy for prolonging pregnancy by at least 48 hours. General pharmacological principles for the clinician regarding drugs in pregnancy are also briefly discussed. In general, while the choice of the best first-line short-term tocolytic drug is not clear, it is evident that use of these agents has a clear place in current obstetric therapeutics.

Keywords: tocolytics, short-term, preterm delivery

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