Short-Term Efficacy of Selective Laser Trabeculoplasty in Omani Eyes with Glaucoma: A Single Institutional Study
Received 28 June 2020
Accepted for publication 6 August 2020
Published 14 September 2020 Volume 2020:14 Pages 2631—2638
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Aisha Al Busaidi,1 Kashinatha Shenoy,1 Sathiya Murthi Panchatcharam,2 Abdullah Al-Mujaini1,3
1Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Oman; 2Research Section, Oman Medical Specialty Board, Muscat, Oman; 3College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, Oman
Correspondence: Aisha Al Busaidi Department of Ophthalmology
Sultan Qaboos University Hospital, PO Box 38, PC 123, Muscat, Oman
Tel +968 24144547
Purpose: There is some evidence suggesting a different nature of response to selective laser trabeculoplasty (SLT) among different races. Therefore, we aimed to assess the short-term efficacy, safety and nature of outcome of SLT in Omani eyes.
Patients and Methods: A retrospective review was performed of patients with open-angle glaucoma (OAG) or ocular hypertension (OHTN) who underwent a single session of 360-degree SLT between January 1, 2017 and December 31, 2018. The main outcome was mean IOP reduction and attainment of treatment success at 5 weeks and 12 weeks post treatment defined as at least 20% IOP reduction from baseline without further medications or interventions. Secondary outcomes were frequency of adverse events and factors predicting success.
Results: A total of 33 eyes of 33 Omani patients who underwent treatment with SLT were analyzed. The nature of response to laser followed a gradual pattern as the mean IOP reduction from baseline was 20.2% (5.21 mm Hg, P < 0.001) at 5 weeks and further enhanced to 27.2% (6.95 mm Hg, P < 0.001) at 12 weeks. Short-term success was achieved in 51.5% and 72.2% of eyes at 5 and 12 weeks, respectively. SLT was most effective in OHTN subgroup and those with higher baseline IOP (both P < 0.001). Side effects were an infrequent occurrence, minor and transient.
Conclusion: The short-term success of SLT in Omani eyes was clinically relevant and comparable to the gradual pattern seen in patients of Indian ancestry. It is a safe therapeutic option in selective Omani eyes.
Keywords: SLT, race, outcome, open-angle glaucoma, ocular hypertension