Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression [Retraction]

He J, Guan J, Liao S, et al. Onco Targets Ther. 2021;14:1–13.

We, the Editor and Publisher of Onco Targets and Therapy are retracting the published article. Since publication, concerns have been raised about the duplication of images in this article with those from other unrelated articles. Specifically,

• The image in Figure 1I, HOS, si-NC, has been duplicated with the image from Figure 2I, SW480, si-NC, from Luo X, Yue M, Li C, Sun D, Wang L. Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer. Onco Targets Ther. 2020;13:12067–12081. https://doi.org/10.2147/OTT.S278582 (RETRACTED).
• The image from Figure 1I, Saos-2, si-CCDC144NL-AS1, and Figure 5D, HOS, si-CCDC144NL-AS1+anti-miR-490-3p, has been duplicated with the image from Figure, 4H, HCT116, si-C1QTNF1-AS1+NC inhibitor and Figure 1H, SW480, si-NC, respectively, from Jin S, Liu Y, Wang W, Li Z. Long Non-Coding RNA C1QTNF1 Antisense RNA 1 Upregulates Hexokinase 2 by Sponging microRNA-484 to Promote the Malignancy of Colorectal Cancer. Cancer Manag Res. 2020;12:12053–12066. https://doi.org/10.2147/CMAR.S262096 (RETRACTED).
• The image from Figure 1H, Saos-2, si-NC, has been duplicated with the image from Figure 1I, HCT116, si-NC from Liu H, Zhang X, Jin X, et al. Long Noncoding RNA VPS9D1-AS1 Sequesters microRNA-525-5p to Promote the Oncogenicity of Colorectal Cancer Cells by Upregulating HMGA1. Cancer Manag Res. 2020;12:9915–9928. https://doi.org/10.2147/CMAR.S273687.
• The image from Figure 3C, HOS, miR-490-3p mimic, has been duplicated with the image from Figure 5E, U-CH2, 2, from Li L, Lv G, Wang B, Ma H. RETRACTED ARTICLE: Long Noncoding RNA LINC00525 Promotes the Aggressive Phenotype of Chordoma Through Acting as a microRNA-505-3p Sponge and Consequently Raising HMGB1 Expression. Onco Targets Ther. 2020;13:9015–9027. https://doi.org/10.2147/OTT.S268678 (RETRACTED).

When approached for an explanation, the authors have been unable to address the concerns raised and have not been able to provide sufficient original data from their study. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The authors listed in this publication have been informed.

We have been informed in our decision-making by our editorial policies and the COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.