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Effect of Doxofylline on Reducing the Inflammatory Response in Mechanically Ventilated Rats with Chronic Obstructive Pulmonary Disease [Retraction]

Authors Liu CY, Wu JH, Chen ZY, Zhang Y, Huang CL, Lin AM, Xu XT, Gao XH

Received 25 May 2023

Accepted for publication 25 May 2023

Published 26 May 2023 Volume 2023:18 Pages 1005—1006

DOI https://doi.org/10.2147/COPD.S422914



Liu CY, Wu JH, Chen ZY, et al. Int J Chron Obstruct Pulmon Dis. 2021;16:2375–2383.

The Editor and Publisher of International Journal of Chronic Obstructive Pulmonary Disease are retracting the published article. Concerns were raised that the western blot results in Figure 6 had been duplicated with those from Figure 4 in Chen Z, Zhang Y, Wu J, Gao X, Huang C, Lin Y, Xu X, Li Y. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021;16:877–885, https://doi.org/10.2147/COPD.S295329. Both sets of western blots are describing results from different studies.

In addition, the image from Figure 2N was found to have been duplicated with the same image from Figure 1N from Chen Zy, Lin Ym, Wu Jh, et al. Effect of doxofylline on pulmonary inflammatory response and oxidative stress during mechanical ventilation in rats with COPD. BMC Pulm Med 22, 66 (2022), https://doi.org/10.1186/s12890-022-01859-6.

The authors did not respond to our queries and as the findings could not be verified the Editor and Publisher made the decision to retract the article. The authors were notified of this decision.

We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.


This retraction relates to this paper


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