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Resolution of vitreomacular traction following intravitreal ranibizumab in cases of ocular toxoplasmosis with choroidal neovascularization

Authors Petrou P, Georgalas I, Markomichelakis N, Vergados I, Gianakaki E, Rouvas A, Karmiris E

Received 29 July 2013

Accepted for publication 6 September 2013

Published 18 October 2013 Volume 2013:9 Pages 391—394


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Petros Petrou,1,2 Ilias Georgalas,2 Nikolaos Markomichelakis,2 Ioannis Vergados,2 Emanuela Gianakaki,2 Alexander Rouvas2

1Moorfields Eye Hospital, London, UK; 2Ophthalmology Department, University of Athens, Athens, Greece

Purpose: To present the occurrence of the resolution of vitreomacular traction following intravitreal ranibizumab in two patients with inflammatory choroidal neovascular (CNV) membrane with a background of ocular toxoplasmosis.
Methods: Interventional case report.
Results: A 21-year-old Caucasian woman and a 52-year-old Caucasian man both presented with vitreomacular traction with coexistent classic CNV membrane and a background of ocular toxoplasmosis. They both received an intravitreal injection of ranibizumab in an effort to control the underlying CNV membrane. A resolution of the vitreomacular traction was observed within 1 week of the intravitreal injection in both cases.
Conclusion: To the best of our knowledge, this is the first reported case of vitreomacular traction resolution in two patients with ocular toxoplasmosis following ranibizumab administration. Of course, further studies are needed in order to adequately support this association.

Keywords: vitreomacular traction, spontaneous resolution, ranibizumab, intravitreal, inflammation

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