Back to Journals » Clinical Ophthalmology » Volume 5

Recurrent corneal ulceration in presence of synthetic microfibrils

Authors Barsam, Patel, Laganowski, Perry H

Published 21 June 2011 Volume 2011:5 Pages 837—839


Review by Single anonymous peer review

Peer reviewer comments 2

A Barsam1, N Patel1, H Laganowski2, HD Perry3
1Moorfields Eye Hospital, London, UK; 2Department of Ophthalmology, Queen Mary's Hospital, Sidcup, Kent, UK; 3Ophthalmic Consultants of Long Island, Nassau University, Long Island, NY, USA

Abstract: Recurrence of microbial keratitis in the presence of protozoal infection is very rare and infrequently reported unless predisposing factors are present. The association of recurrent microbial keratitis and synthetic microfibrils has never previously been reported to our knowledge. This single interventional case study describes the clinical course and treatment of a contact lens wearer who was treated for Acanthamoeba keratitis with superinfection from bacterial organisms in the presence of synthetic microfibrils. The presence of synthetic fibrils on a corneal ulcer base may act as a nidus for pathological organisms and interfere with normal corneal healing. This may result in infection recurrence and the growth of resistant opportunistic organisms.

Keywords: Acanthamoeba, microbial keratitis, cornea ulcer, contact lens infection, synthetic microfibrils

Creative Commons License © 2011 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.